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2-{3-[6-{[4-(trifluoromethoxy)phenyl]sulfonyl}-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl}propan-2-ol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1034152-95-8

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1034152-95-8 Usage

Properties

Sulfonamide group
Pyridobenzodiazepine core
Oxadiazole ring
Trifluoromethyl and trifluoromethoxy substituents
High lipophilicity
High metabolic stability
Potential pharmacological applications
Valuable for drug discovery and development research

Check Digit Verification of cas no

The CAS Registry Mumber 1034152-95-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,4,1,5 and 2 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1034152-95:
(9*1)+(8*0)+(7*3)+(6*4)+(5*1)+(4*5)+(3*2)+(2*9)+(1*5)=108
108 % 10 = 8
So 1034152-95-8 is a valid CAS Registry Number.

1034152-95-8Relevant academic research and scientific papers

Discovery of MK-7725, a potent, selective bombesin receptor subtype-3 agonist for the treatment of obesity

Chobanian, Harry R.,Guo, Yan,Liu, Ping,Chioda, Marc,Lanza, Thomas J.,Chang, Linda,Kelly, Theresa M.,Kan, Yanqing,Palyha, Oksana,Guan, Xiao-Ming,Marsh, Donald J.,Metzger, Joseph M.,Gorski, Judith N.,Raustad, Kate,Wang, Sheng-Ping,Strack, Alison M.,Miller, Randy,Pang, Jianmei,Madeira, Maria,Lyons, Kathy,Dragovic, Jasminka,Reitman, Marc L.,Nargund, Ravi P.,Lin, Linus S.

supporting information; experimental part, p. 252 - 256 (2012/07/13)

Extensive structure-activity relationship studies of a series derived from atropisomer 1, a previously described chiral benzodiazepine sulfonamide series, led to a potent, brain penetrant and selective compound with excellent preclinical pharmacokinetic a

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