103419-79-0

Basic information

• Product Name: B-L-FUCOPYRANOSYLAMINE
• Synonyms: 1-AMINO-1,6-DIDEOXY-L-GALACTOSE;1-AMINO-1-DEOXY-L-FUCOSE;L-FUCOSYLAMINE*;1-Amino-1,6-dideoxy-L-galactose,1-Amino-1-deoxy-L-fucose;-L-Fucopyranosylamine;6-Deoxy-a-L-galactopyranosylaMine;6-Deoxy-alpha-L-galactopyranosylamine;B-L-FUCOPYRANOSYLAMINE
• CAS NO: 103419-79-0
• Molecular Formula: C6H13NO4
• Molecular Weight: 163.17
• Product Categories: Carbohydrates & Derivatives
• Mol File: 103419-79-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 142-145 °C
• Boiling Point: 331.5°C at 760 mmHg
• Flash Point: 154.3°C
• Appearance: /
• Density: 1.406g/cm³
• Vapor Pressure: 1.12E-05mmHg at 25°C
• Refractive Index: 1.563
• Storage Temp.: −20°C
• Solubility: Methanol, Water
• Stability: Unstable-Store in Freezer at -20°C
• CAS DataBase Reference: B-L-FUCOPYRANOSYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: B-L-FUCOPYRANOSYLAMINE(103419-79-0)
• EPA Substance Registry System: B-L-FUCOPYRANOSYLAMINE(103419-79-0)

Safety Data

• Hazardous Substances Data: 103419-79-0(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

β-L-Fucopyranosylamine (cas# 103419-79-0) is a compound useful in organic synthesis.

InChI:InChI=1/C6H13NO4/c1-2-3(8)4(9)5(10)6(7)11-2/h2-6,8-10H,7H2,1H3

Upstream product

• 2438-80-4 L-Fucose 
• 6696-41-9 alpha-L-fucose 

Relevant articles and documents

Designing Two-Dimensional Nanosheets for Improving Drug Delivery to Fucose-Receptor-Overexpressing Cancer Cells

Targeted drug delivery has shown promise in improving the therapeutic efficacy of anticancer drugs. Gemcitabine hydrochloride (GEM) is a broad-range chemotherapeutic agent for the treatment of various cancers. However, systemic use of free GEM is restricted because of its poor physicochemical properties and nonspecific drug delivery, resulting in dose-dependent adverse effects. In this study, a fucose-conjugated graphene oxide (GO)-based smart targeted nanocarrier system was designed to provide high loading, sustained release, and targeted high concentrations of GEM to cancer cells. Fucose-conjugated GO nanosheets (FGONS) and GEM-loaded fucose-conjugated GO nanosheets (GEM-FGONS) were prepared and characterized by various techniques. About 36.2 % of GEM was loaded to the FGONS, which showed a pH-dependent release over a period of 48 h. A colloidal suspension of GEM-FGONS was found to be physiochemically stable for up to 96 h. In cytotoxicity studies, GEM-FGONS demonstrated time- and dose-dependent high toxicities on fucose-receptor-overexpressing MDA-MB-231 human breast cancer cells and A549 human lung cancer cells. Moreover, targeted formulations were more efficacious than non-targeted or free GEM. Overall, bioconjugation of fucose helps in the stabilizing and targeting of graphene oxide nanosheets.