10342-87-7

Usage

Uses

Used in Pharmaceutical Research:
1-(4-(4-hydroxypiperidin-1-yl)phenyl)ethanone is used as a chemical compound for pharmaceutical research due to its potential biological activity. The presence of the piperidine and phenyl groups in the molecule indicates that it may have interactions with biological targets, such as receptors or enzymes, which could be harnessed for therapeutic purposes.
Used in Synthesis of Other Compounds:
1-(4-(4-hydroxypiperidin-1-yl)phenyl)ethanone is also used as a building block in the synthesis of other compounds. Its unique structure and functional groups make it a valuable component in the development of new pharmaceuticals or other chemical products with specific applications.
Further research and testing are necessary to fully understand the properties and potential uses of 1-(4-(4-hydroxypiperidin-1-yl)phenyl)ethanone, as its current applications are based on its structural characteristics and the possibility of its interaction with biological targets.

Upstream product

• 5382-16-1 4-HYDROXYPIPERIDINE 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 10342-85-5 4-piperidinoacetophenone 

Downstream Products

• 79421-48-0 1-(4-Acetylphenyl)piperidin-4-on 

Relevant academic research and scientific papers

A new paradigm for biohydroxylation by Beauveria bassiana ATCC 7159

The biohydroxylation of a series of amides and related amino, keto and hydrocarbon substrates by the fungal biocatalyst Beauveria bassiana ATCC 7159 has been examined. The product distributions, together with data obtained from selective inhibition experiments using the cyt.P-450 inhibitors isosafrole, 1-aminobenzotriazole and phenylacetylene, suggest that B. bassiana contains a range of hydroxylase enzymes with different substrate specificities. A paradigm is presented for the interpretation of the results of microbial hydroxylation and for the application of existing active site models for B. bassiana.

Biooxidations of some N-Arylpiperidines and Related Compounds using Beauveria sulfurescens

Beauveria sulfurescens ATCC 7159 oxidized the N-arylamines 3, 4, 7, 13, 18, 20, 22 at the 4-position with good selectivity and in 34 - 66percent yield.

Selective Oxygenation of Adamantanes and Other Substrates by Beauveria sulfurescens

Oxygenation of N-(2-adamantyl)benzamide (7) with the fungus Beauveria sulfurescens (ATCC 7159) gave 4β-benzamidoadamantan-1-ol (8), whose structure was determined by X-ray crystallography.Oxygenation of N-methyl-N-(4-methyleneadamant-1-yl)benzamide (9) gave two products, the β-epoxide 10 and the 5-hydroxy β-epoxide 11, the latter structure determined by X-ray crystallography.Oxygenation of 4-methylene-1-(p-toluenesulfonyl)piperidne (12) gave 4-hydroxy-4-(hydroxymethyl)-1-(p-toluenesulfonyl)piperidine (14) and of 4-piperidinoacetophenone (13) gave 4-(4-hydroxypiperidino)acetophenone (15).