1034292-98-2Relevant academic research and scientific papers
1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin
Odlo, Kristin,Hentzen, Jean,dit Chabert, Jeremie Fournier,Ducki, Sylvie,Gani, Osman A.B.S.M.,Sylte, Ingebrigt,Skrede, Martina,Florenes, Vivi Ann,Hansen, Trond Vidar
, p. 4829 - 4838 (2008/12/22)
A series of cis-restricted 1,5-disubstituted 1,2,3-triazole analogues of combretastatin A-4 (1) have been prepared. The triazole 12f, 2-methoxy-5-(1-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazol-5-yl)aniline, displayed potent cytotoxic activity against severa
