1034305-23-1

Basic information

• Product Name: Methyl 1-C-[3-(benzo[b]thien-2-ylMethyl)-4-fluorophenyl]-
• Synonyms: Methyl 1-C-[3-(benzo[b]thien-2-ylMethyl)-4-fluorophenyl]-;Methyl 1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-alpha-D-glucopyranoside;(2S,3R,4S,5S,6R)-2-(3-(benzo[b]thiophen-2-ylMethyl)-4-fluorophenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol;Ipragliflozin impurity A (C7);Methyl 1-C-[3-(1-benzothien-2-ylmethyl)-4-fluorophenyl]-alpha-glucopyranoside;Methyl 1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-α-D-glucopyranoside
• CAS NO: 1034305-23-1
• Molecular Formula: C₂₂H₂₃FO₆S
• Molecular Weight: 434.4778232
• EINECS: -0
• Mol File: 1034305-23-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Methyl 1-C-[3-(benzo[b]thien-2-ylMethyl)-4-fluorophenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 1-C-[3-(benzo[b]thien-2-ylMethyl)-4-fluorophenyl]-(1034305-23-1)
• EPA Substance Registry System: Methyl 1-C-[3-(benzo[b]thien-2-ylMethyl)-4-fluorophenyl]-(1034305-23-1)

Safety Data

• Hazardous Substances Data: 1034305-23-1(Hazardous Substances Data)

Usage

General Description

Methyl 1-C-[3-(benzo[b]thien-2-ylMethyl)-4-fluorophenyl]- is a chemical compound with a complex molecular structure. It contains a methyl group, fluorophenyl group, and benzo[b]thien-2-ylMethyl group, which are all connected to a central carbon atom. Methyl 1-C-[3-(benzo[b]thien-2-ylMethyl)-4-fluorophenyl]- likely has pharmaceutical or industrial applications, potentially as a molecular scaffold for drug development or as a building block for organic synthesis. The presence of the fluorophenyl and benzo[b]thien-2-ylMethyl groups suggests that it may have specific chemical and biological properties. Further research and testing would be needed to determine the exact characteristics and potential uses of this chemical.

Upstream product

• 67-56-1 methanol 
• 1034305-17-3 2-[(5-bromo-2-fluorophenyl)methyl]-1-benzothiophene 
• 32469-28-6 (3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one 

Downstream Products

• 1034305-27-5 methyl 2,3,4,6-tetra-O-acetyl-1-C-[3-(1-benzothien-2-ylmethyl)-4-fluorophenyl]-α-glucopyranoside 

Relevant articles and documents

Preparing methods of ipragliflozin intermediates

The invention discloses preparing methods of ipragliflozin intermediates. The methods includes preparing methods for 2-(3-benzo[B]thien-2-ylmethyl-4-fluorophenyl)-3,4,5-tris(trimethylsiloxy)-6-trimethylsiloxymethyl-tetrahydro-pyran-2-ol (a compound 3) and (1S)-2,3,4,6-tetraacetoxy-1,5-anhydro-1-[3-(1-benzothiophen-2-yl-methyl)-4-fluorophenyl]-D-glucitol (a compound 6). Under the premise of controlling the temperature of a reaction solution to be not higher than -60 DEG C, n-butyllithium should be added dropwise as soon as possible, and the higher the adding speed of the n-butyllithium is, theless F-ortho-position substituted side products of the compound 3 are, thus ensuring purity of the compound 3 and directly influencing the yield of the compound 6 finally prepared. Through scale-up, the methods are free of scale-up effects, and are suitable for industrial production.

METHOD FOR PRODUCING C-GLYCOSIDE DERIVATIVE AND SYNTHETIC INTERMEDIATE THEREOF

The present invention provides a method for producing a C-glycoside derivative, which can produce the C-glycoside derivative at a high yield and at a low cost, which conforms to environmental protection, and which is applicable industrially. The C-glycoside derivative is useful for treating and preventing diabetes such as insulin-dependent diabetes (type 1 diabetes), non-insulin-dependent diabetes (type 2 diabetes) and the like and various diabetes-related diseases including insulin-resistant diseases and obesity.