103437-70-3Relevant academic research and scientific papers
Easy Access to 5-(E)-Alkynylidene Tetrahydro-2 Furanones by a Palladium Catalyzed Process
Bouyssi, Didier,Gore, Jacques,Balme, Genevieve
, p. 2811 - 2814 (1992)
Biologically active ynenol lactones 1 are stereospecifically obtained when γ-acetylenic carboxylates are reacted with 1-bromo 1-alkynes in the presence of a palladium(0)-phosphine complex.The reaction is effective only with the potassium carboxylate and the nature of the phosphine is essential for the cyclisation process.
Ynenol Lactones: Synthesis and Investigation of Reactions Relevant to Their Inactivation of Serine Proteases
Spencer, Robin W.,Tam, Tim Fat,Thomas, Everton,Robinson, Valerie J.,Krantz, Allen
, p. 5589 - 5597 (2007/10/02)
The syntheses of ynenol lactones which are designed as serine protease suicide substrates have b
