103440-60-4Relevant academic research and scientific papers
SYNTHESIS OF SMALL MOLECULES INSPIRED BY PHOMOXANTHONE A
-
, (2022/02/28)
Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.
Synthesis and Anticancer Activity of Structure Simplified Naturally Inspired Dimeric Chromenone Derivatives
Ali, Rameez,Guan, Yong,Leveille, Alexandria N.,Vaughn, Elizabeth,Parelkar, Sangram,Thompson, Paul R.,Mattson, Anita E.
, p. 6917 - 6929 (2019/09/06)
Select dimeric chromenones exhibit low micromolar cytotoxicity toward lymphoma and leukemia cell lines, L5178Y and HL60, respectively. The bioactive dimeric chromenones were identified from a focused library of structurally simplified derivatives of natur
