103441-24-3Relevant academic research and scientific papers
Transition metal-free protodecarboxylation of electron rich aromatic acids under mild conditions
Fang, Jingxian,Wang, Dangui,Deng, Guo-Jun,Gong, Hang
, p. 4503 - 4506 (2017)
A mild and practical method for the transition metal-free protodecarboxylation of aromatic acids using readily available and safe sodium persulfate as initiator was described. This environment-friendly decarboxylation approach was performed at 60 °C in ethanol and could easily scale up to the gram level with a good yield. In Particular, the tandem reactions of decarboxylation and halogenation were achieved by the addition of the corresponding halogenating reagents to the reaction system.
