103445-11-0

Basic information

• Product Name: C₁₃₂H₂₁₁Cl₂O₂₃PSi₂
• Synonyms: C₁₃₂H₂₁₁Cl₂O₂₃PSi₂
• CAS NO: 103445-11-0
• Molecular Weight: 2324.16
• Mol File: 103445-11-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₃₂H₂₁₁Cl₂O₂₃PSi₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃₂H₂₁₁Cl₂O₂₃PSi₂(103445-11-0)
• EPA Substance Registry System: C₁₃₂H₂₁₁Cl₂O₂₃PSi₂(103445-11-0)

Safety Data

• Hazardous Substances Data: 103445-11-0(Hazardous Substances Data)

Upstream product

• 102916-98-3 1,2-di-O-oleoyl-sn-glycero-3-phospho-(2,4-dichlorophenol) triethylammonium salt 
• 78841-89-1 3-O-<2-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-3,4-O-(tetraisopropyldisiloxane-1,3-diyl)-α-D-glucopyranosyl>-1,2-di-O-palmitoyl-sn-glycerol 
• 102916-98-3 (Z)-Octadec-9-enoic acid (R)-2-[(2,4-dichloro-phenoxy)-hydroxy-phosphoryloxy]-1-((Z)-octadec-9-enoyloxymethyl)-ethyl ester; compound with triethyl-amine 

Downstream Products

• 102904-92-7 C₁₂₆H₂₀₉O₂₃PSi₂ 

Relevant articles and documents

SYNTHESIS OF STREPTOCOCCI PHOSPHATIDYL-α-DIGLUCOSYLDIGLYCERIDE AND RELATED GLYCOLIPIDS. APPLICATION OF THE TETRAISOPROPYLDISILOXANE-1,3-DIYL (TIPS) PROTECTING GROUP IN SUGAR CHEMISTRY. PART V

A short and convenient synthesis of phosphatidyl-α-diglucosyldiglyceride (i. e. compound 8d) and two related Streptococci glycolipids (i. e. compounds 6a and 6b) will be presented. 4',6'-Tetraisopropyl-disiloxane-1,3-diyl (TIPS) protected α-glucosyl diglyceride (i. e. compound 2) turned out to be a suitable protected precursor.Thus, compound 2 was selectively condensed with glucosyl bromide 3 to afford 4.Removal of the protecting groups from 4 gave glycolipid 6a.The "dynamic" properties of the TIPS protecting group were utilized to convert 4',6'-TIPS protected 4 into 3',4'-TIPS protected derivative 5a.Compound 5a could then be condensed with either a stearoyl fatty acid or a phosphatidyl moiety to give the fully protected derivatives 5c and 8a, respectively.Finally, removal of all the protecting groups from 5c and 8a afforded the glycolipid 6b and glycophospholipid 8d, respectively.