1034738-41-4

Basic information

• Product Name: 1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid
• Synonyms: 1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid
• CAS NO: 1034738-41-4
• Molecular Formula: C₁₁H₁₀ClN₃O₂
• Molecular Weight: 251.669
• Mol File: 1034738-41-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid(1034738-41-4)
• EPA Substance Registry System: 1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid(1034738-41-4)

Safety Data

• Hazardous Substances Data: 1034738-41-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid is used as an active pharmaceutical ingredient for its antimicrobial, antiviral, and anticancer properties. Its diverse biological activities make it a promising candidate for the development of new drugs to combat various diseases.
Used in Chemical Research and Development:
In the field of chemical research and development, 1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid is used as a key building block for the synthesis of more complex molecules with potential applications in various industries.
Used in Metal Coordination:
1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid is used as a ligand for metal coordination, which has been studied for its potential use in metal-organic frameworks and catalysis. Its ability to form stable complexes with metals makes it a valuable compound in the development of new materials and catalysts.
Used in Material Science:
In material science, 1-(2-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid is used for the development of new materials with unique properties, such as metal-organic frameworks, which have potential applications in gas storage, separation, and catalysis.

Upstream product

• 1093236-55-5 C₁₃H₁₄ClN₃O₂ 

Downstream Products

• 1093237-05-8 C₁₁H₉Cl₂N₃O 

Relevant articles and documents

TRIAZOLE DERIVATIVES AS SCD INHIBITORS

The present invention relates to substituted triazole compounds of the formula (I): and salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for inhibiting SCD activity.

1,2,3-Triazol-carboxanilides and 1,2,3-triazol-(N-benzyl)-carboxamides as BK-potassium channel activators. XII

The chemical structures of many synthetic activators of large-conductance calcium-activated potassium channels (BK channels) satisfy a simple pharmacophore model, consisting of two appropriately substituted phenyl rings connected by a linker of a heterogeneous nature. In this paper, a series of new compounds with modifications of the linker portion of the above pharmacophore are described. In particular, in these new derivatives, the linker portion is represented by a 1,2,3-triazole-carboxamide group, which can be viewed as a combination of two different kinds of linker, independently used in previous series of BK-openers: the amide function and the 1,2,3-triazole ring. The overall finding of this study indicated that the triazole-carboxamide derivatives were generally poorly effective and that this structural modification of the linker is deleterious for activity on BK channels. Therefore, it can be hypothesized that the increase of the steric hindrance of the linker and/or the increase of the distance between the two aromatic portions are negative for the interaction with the biological target.