103476-21-7 Usage
Uses
DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt hydrate has been used in drug treatment to study its effect on mTORC1 regulation. It has also been used to compare the acylomes of two reactive acyl-CoA species, like HMG-CoA and?glutaryl-CoA.
General Description
DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)?is obtained from acetyl-CoA?and?acetoacetyl-CoA during condensation with the help of HMG-CoA synthase.
Biochem/physiol Actions
DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) is a substrate used to study the specificity and kinetics of the enzyme 3-hydroxyl-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase. HMG-CoA is the key intermediate in the biosynthsis of terpenes and ketone bodies. Its metabolism is the target of statin drugs used to control cholesterol levels.
Check Digit Verification of cas no
The CAS Registry Mumber 103476-21-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,4,7 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 103476-21:
(8*1)+(7*0)+(6*3)+(5*4)+(4*7)+(3*6)+(2*2)+(1*1)=97
97 % 10 = 7
So 103476-21-7 is a valid CAS Registry Number.
InChI:InChI=1/C27H44N7O20P3S.Na/c1-26(2,21(40)24(41)30-5-4-15(35)29-6-7-58-17(38)9-27(3,42)8-16(36)37)11-51-57(48,49)54-56(46,47)50-10-14-20(53-55(43,44)45)19(39)25(52-14)34-13-33-18-22(28)31-12-32-23(18)34;/h12-14,19-21,25,39-40,42H,4-11H2,1-3H3,(H,29,35)(H,30,41)(H,36,37)(H,46,47)(H,48,49)(H2,28,31,32)(H2,43,44,45);
