103476-53-5Relevant academic research and scientific papers
Total Synthesis of the Hamigerans
Li, Xiaojun,Xue, Dongsheng,Wang, Cheng,Gao, Shuanhu
, p. 9942 - 9946 (2016)
The first total synthesis of hamigerans D, G, L, and N–Q has been accomplished. A convergent approach was used to build the basic tricarbocyclic ring system bearing a 5-6-6 structure. A sequence of oxidative cleavage, homologation, and ring regeneration provided access to the 5-7-6 skeleton of hamigeran G. Based on the biogenetic hypothesis, elegant and highly efficient biomimetic transformations of hamigeran G into hamigerans D, N–Q, and L were achieved.
Progress toward the Total Synthesis of Gukulenin A: Photochemically Triggered Two-Carbon Ring Expansion Key to α-Tropolonic Ether Synthesis
Tymann, David,Bednarzick, Ulf,Iovkova-Berends, Ljuba,Hiersemann, Martin
, p. 4072 - 4076 (2018)
The ex-chiral-pool synthesis of an advanced gukulenin A precursor from (-)-piperitone is revealed. Key C/C connecting maneuvers to the synthesis of a C2 dissymmetric bis(α-tropolonic) ether building block are a ring-contracting Meinwald rearrangement, a photochemically triggered two-carbon ring expansion, and a homodimerization by cross-metathesis.
Isolation, structural assignment and insecticidal activity of (-)-(1S,2R,3R,4S)-1,2-epoxy-1-methyl-4-(1-methylethyl)-cyclohex-3-yl acetate, a natural product from Minthostachys tomentosa
Cantin, Angel,Lull, Cristina,Primo, Jaime,Miranda, Miguel A.,Primo-Yufera, Eduardo
, p. 677 - 683 (2007/10/03)
(-)-(1S,2R,3R,4S)-1,2-Epoxy-1-methyl-4-(1-methylethyl)-cyclohex-3-yl acetate has previously been identified as the active compound of Minthostachys tomentosa responsible for the insecticidal activity against Oncopeltus fasciatus. Its structure was initial
