103479-19-2Relevant academic research and scientific papers
Synthesis method of ortho-aryl substituted tertiary phosphine compound
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Paragraph 0027-0031; 0064-0067, (2021/01/29)
The invention discloses a synthesis method of an ortho-aryl modified tertiary phosphine compound, and belongs to the technical field of organic synthesis. The aryl-modified tertiary phosphine compound3 is prepared from biphenyl 2diphenylphosphine 1 and a
Rhodium(I)-Catalyzed Tertiary Phosphine Directed C?H Arylation: Rapid Construction of Ligand Libraries
Qiu, Xiaodong,Wang, Minyan,Zhao, Yue,Shi, Zhuangzhi
supporting information, p. 7233 - 7237 (2017/06/13)
Modification of commercially available monophosphine ligands with either aryl bromides or chlorides by rhodium(I)-catalyzed, tertiary phosphine directed C?H activation is described. A series of ligand libraries containing mono- and diaryl-substituted groups, having different steric and electronic properties, were obtained in high yields. Based on the outstanding properties of their parent scaffolds, the modified ligands have been found to be powerful in organic reactions.
Preparation method for aryl-substituted biphenyl, pyrrole, indol or binaphthyl monophosphine ligand
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Paragraph 0039; 0040, (2017/08/29)
The invention discloses a preparation method for a new-style monophosphine ligand. The method comprises the following process: (a) by taking a commercialized biphenyl, pyrrole, indol or binaphthyl monophosphine ligand as a raw material, under the protection of inert gas, controlling the reaction temperature to be 70-150 DEG C in an organic solution under the participation of an inorganic base, and carrying out monovalent rhodium catalysis on the raw material and an aromatic halogenated compound to prepare the new-style aryl-substituted biphenyl, pyrrole, indol or binaphthyl monophosphine ligand. The synthetic route is not reported in literature, and the raw material is cheap and easily available; and the unit operation is simple, and the requirement on equipment is low, so that the preparation method is suitable for quickly constructing a new-style monophosphine ligand library.
