1035-71-8 Usage
General Description
5α-Androstane-3,16-dione is a steroid hormone and an androgenic compound. It is a precursor to the androgenic hormone, dihydrotestosterone (DHT), and is involved in various biological processes in the body, including the development and maintenance of male sexual characteristics. It is also known to play a role in the regulation of sexual function, muscle growth, and overall physical performance. Additionally, 5α-Androstane-3,16-dione has been used in scientific research and medical treatments for conditions related to androgen deficiency and hormone imbalance.
Check Digit Verification of cas no
The CAS Registry Mumber 1035-71-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,3 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1035-71:
(6*1)+(5*0)+(4*3)+(3*5)+(2*7)+(1*1)=48
48 % 10 = 8
So 1035-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H28O2/c1-18-7-6-16-15(17(18)10-14(21)11-18)4-3-12-9-13(20)5-8-19(12,16)2/h12,15-17H,3-11H2,1-2H3/t12-,15+,16-,17-,18+,19-/m0/s1
1035-71-8Relevant articles and documents
Deoxygenation of steroidal ring-D 16,17-ketols with trimethylsilyl iodide
Nagaoka, Masao,Nagasawa, Etsuko,Numazawa, Mitsuteru
, p. 1857 - 1861 (2007/10/03)
Reaction of various steroidal 16,17-ketols, 16α-hydroxy-17-ketones 1- 3, and 15, 16β-hydroxy-17-ketone 4, and 17β-hydroxy-16-ketones 5-7, and 17, along with methyl ethers of 16α- and 17β-ketols 1 and 5, with an excess of trimethylsilyl iodide (TMSI) or with HI in CHCl3, produced the deoxygenated products, a mixture of the corresponding 17- and 16-ketones, in low to quantitative yields, in which the 17-ketone was the major product in each ease. When the 16β-deuterated 16α-ketol 3 and the 17α-deuterated 17β- ketol 7 were reacted with TMSI for a brief period (15 min), the deuterium content at C-16β and C-17α of the recovered steroids 3 and 7 was reduced by 17 and 35%, respectively. The present results indicate that the deoxygenation proceeds not only through a direct iodination pathway producing α-iodoketone but also through other reaction pathways.
