1035-71-8 Usage
Uses
Used in Pharmaceutical Industry:
5α-Androstane-3,16-dione is used as a pharmaceutical ingredient for the treatment of conditions related to androgen deficiency and hormone imbalance. It helps in addressing issues such as low libido, muscle wasting, and fatigue associated with androgen deficiency.
Used in Scientific Research:
5α-Androstane-3,16-dione is used as a research compound in the study of androgen biology, hormone regulation, and the development of new therapies for hormone-related conditions. It aids researchers in understanding the mechanisms of action and potential applications of androgenic compounds in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 1035-71-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,3 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1035-71:
(6*1)+(5*0)+(4*3)+(3*5)+(2*7)+(1*1)=48
48 % 10 = 8
So 1035-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H28O2/c1-18-7-6-16-15(17(18)10-14(21)11-18)4-3-12-9-13(20)5-8-19(12,16)2/h12,15-17H,3-11H2,1-2H3/t12-,15+,16-,17-,18+,19-/m0/s1
1035-71-8Relevant academic research and scientific papers
Deoxygenation of steroidal ring-D 16,17-ketols with trimethylsilyl iodide
Nagaoka, Masao,Nagasawa, Etsuko,Numazawa, Mitsuteru
, p. 1857 - 1861 (2007/10/03)
Reaction of various steroidal 16,17-ketols, 16α-hydroxy-17-ketones 1- 3, and 15, 16β-hydroxy-17-ketone 4, and 17β-hydroxy-16-ketones 5-7, and 17, along with methyl ethers of 16α- and 17β-ketols 1 and 5, with an excess of trimethylsilyl iodide (TMSI) or with HI in CHCl3, produced the deoxygenated products, a mixture of the corresponding 17- and 16-ketones, in low to quantitative yields, in which the 17-ketone was the major product in each ease. When the 16β-deuterated 16α-ketol 3 and the 17α-deuterated 17β- ketol 7 were reacted with TMSI for a brief period (15 min), the deuterium content at C-16β and C-17α of the recovered steroids 3 and 7 was reduced by 17 and 35%, respectively. The present results indicate that the deoxygenation proceeds not only through a direct iodination pathway producing α-iodoketone but also through other reaction pathways.
