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1035094-10-0

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1035094-10-0 Usage

Uses

A labelled synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time.

Check Digit Verification of cas no

The CAS Registry Mumber 1035094-10-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,5,0,9 and 4 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1035094-10:
(9*1)+(8*0)+(7*3)+(6*5)+(5*0)+(4*9)+(3*4)+(2*1)+(1*0)=110
110 % 10 = 0
So 1035094-10-0 is a valid CAS Registry Number.

1035094-10-0Downstream Products

1035094-10-0Relevant articles and documents

PROSTACYCLIN DERIVATIVES

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, (2011/02/24)

This invention relates to novel prostacyclin derivatives and acceptable salts thereof. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions benefic

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