1035113-20-2

Upstream product

• 146621-74-1 acetoxybrevifoliol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1035113-18-8 C₃₉H₅₆O₁₁Si 

Downstream Products

• 1035113-21-3 C₃₁H₃₆O₉ 
• 1035113-22-4 C₃₃H₄₀O₁₁ 
• 1440522-38-2 C₄₇H₄₉NO₁₂ 
• 1440522-40-6 C₄₉H₅₃NO₁₄ 
• 1440522-39-3 C₄₅H₅₃NO₁₃ 
• 1440522-41-7 C₄₇H₅₇NO₁₅ 
• 1449566-27-1 C₅₁H₅₇NO₁₃ 

Relevant academic research and scientific papers

Dual-functional abeo-taxane derivatives destabilizing microtubule equilibrium and inhibiting NF-κB activation

Taxchinin A, with a 11(15→1)-abeo-taxane skeleton, is a major, but inactive taxoid contained in leaves of Taxus chinensis. In our design of dual-functional antitumor abeo-taxane derivatives, two fragments from antitumor agents with different molecular tar

Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol

Twenty-one derivatives of taxchinin A (1) and brevifoliol (2) were synthesized and evaluated for cytotoxicity against human non-small lung cancer (A549) cell line. Nine derivatives showed potent activity with IC50 values from 0.48 to 6.22 μM. 5