103517-84-6

Upstream product

• 719-80-2 Ethyl diphenylphosphinite 
• 1831-63-6 diphenylphosphorylacetic acid 
• 103517-90-4 N'-[1-Chloromethyl-2-(diphenyl-phosphinoyl)-eth-(E)-ylidene]-hydrazinecarboxylic acid methyl ester 
• 103518-00-9 N'-[2-(Diphenyl-phosphinoyl)-1-(diphenyl-phosphinoylmethyl)-ethylidene]-hydrazinecarboxylic acid methyl ester 

Downstream Products

• 1262149-23-4 bis(diphenylphosphorylmethyl)ketone ((diphenylphosphoryl)acetyl)hydrazone 

Relevant academic research and scientific papers

(CF3CO)2O/CF3so3H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones

A very simple and convenient reaction for 1,3-diketone preparation from carboxylic acids and aromatic ketones in TFAA/TfOH system is described. When the β-phenylpropionic acids were used as starting materials, they initially gave 1-indanones and then underwent further acylation with the formation of 2-(β-phenylpropionyl)-1-indanones as the main reaction products. In addition, the application of the proposed protocol allowed for the synthesis of selected polysubstituted pyrazoles in a one-pot procedure directly from acids and ketones.

An Efficient Synthesis of Dialkyl 2-Oxoalkanephosphonates and Diphenyl-2-oxoalkylphosphine Oxides from 1-Chloralkyl Ketones

The synthesis of dialkyl 2-oxoalkanephosphonates and diphenyl-2-oxoalkylphosphine oxides, via an Arbuzov reaction of trialkyl phosphites or ethoxydiphenylphosphine with methoxycarbonylhydrazono derivatives of 1-chloroalkyl ketones followed by carbonyl deprotection, is described.