1035222-58-2

Upstream product

• 1035222-55-9 (3S,6R,7S)-1-benzyl-6-bromo-7-methoxy-3-(trifluoroacetamido)-azepan-2-one 
• 1035222-56-0 (3S,6R,7S)-1-benzyl-6-iodo-7-methoxy-3-(trifluoroacetamido)-azepan-2-one 

Downstream Products

• 1035222-69-5 C₁₆H₁₉F₃N₂O₅ 
• 1035222-62-8 (S)-1-benzyl-3-(trifluoroacetamido)-2,3,4,7-tetrahydro-1H-azepin-2-one 

Relevant academic research and scientific papers

Diastereoselective additions to (3S)-3-aminodehydrocaprolactams: Development of a versatile synthesis of new substituted cyclic L-lysines

Easily obtained cyclic 6,7-dehydro-L-lysine was employed as starting template to generate variously substituted enantiopure 3-aminocaprolactams. syn-Dihydroxylation, hydroxymethoxylation, halomethoxylation and subsequent eliminations were performed with this starting enelactam, thus leading, in regio- and stereoselective manners, to new mono-, di- and trisubstituted 3-aminocaprolactams. Structural and mechanistic aspects of these reactions, as well as the origin of the high diastereoselectivities observed in this study are discussed. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.