1035327-97-9Relevant academic research and scientific papers
Synthesis of stable isoxazolines by [3+2] cycloaddition of oxaziridines with alkynes
Fabio, Marilena,Ronzini, Ludovico,Troisi, Luigino
, p. 4979 - 4984 (2008/09/21)
N-Alkyl substituted oxaziridines undergo a [3+2] cycloaddition reaction with a variety of terminal alkynes to give the product isoxazolines, whose stability appears to depend on the electronic properties of the groups on the C-3 and C-5 positions. The presence of an electron withdrawing group on C-5 and/or an electron donating group on C-3 causes isomerization of the isoxazolines to β-amino enones.
