1035587-74-6Relevant academic research and scientific papers
Synthesis and biological evaluations of new pyrrolo[2,3-b]pyrimidine as SDI analogs
Guillard, Jerome,Viaud-Massuard, Marie-Claude
, p. 1163 - 1189 (2008/12/20)
The synthesis of new pyrrolo[2,3-d]pyrimidines variously substituted on the N-1 and C-2 atoms are described. Access to these compounds, which have modest activity compared with the first inhibitor SDI, involves, as the key step, the formation of a pyrrolopyrimidine skeleton from the 5-amino-2-(methoxymethyl)pyrimidine.
