1035609-29-0

Basic information

• Product Name: N-[(2S,3R)-2,3-dihydroxy-4-phenylbutanoyl]-L-leucine methyl ester
• Synonyms: N-[(2S,3R)-2,3-dihydroxy-4-phenylbutanoyl]-L-leucine methyl ester
• CAS NO: 1035609-29-0
• Molecular Weight: 323.389
• Mol File: 1035609-29-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(2S,3R)-2,3-dihydroxy-4-phenylbutanoyl]-L-leucine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(2S,3R)-2,3-dihydroxy-4-phenylbutanoyl]-L-leucine methyl ester(1035609-29-0)
• EPA Substance Registry System: N-[(2S,3R)-2,3-dihydroxy-4-phenylbutanoyl]-L-leucine methyl ester(1035609-29-0)

Safety Data

• Hazardous Substances Data: 1035609-29-0(Hazardous Substances Data)

Upstream product

• 1035609-27-8 C₁₀H₁₂O₄ 
• 7517-19-3 methyl (L)-leucinate hydrochloride 

Relevant articles and documents

Degradation-promoters of cellular inhibitor of apoptosis protein 1 based on bestatin and actinonin

A series of hybrid compounds of bestatin (1) and actinonin (3), which promote degradation of cellular inhibitor of apoptosis protein 1 (cIAP1), were designed and synthesized. Structure-activity relationship studies indicated that absolute configuration, hydrophobicity at the α-position of the internal amide carbonyl group, and the presence of a small substituent at the α-position of the ester group are important factors for the expression of potent cIAP1 degradation-promoting activity. HAB-5A (30b) showed the most potent activity (IC50 = 0.53 μM) among the compounds prepared.