1035619-60-3Relevant academic research and scientific papers
A convenient methodology for the chemoselective reduction of a wide variety of functionalized alkenes
Babler, James H.,White, Nicholas A.
, p. 439 - 441 (2010)
An efficient method to effect chemoselective reduction of alkenes (including trisubstituted olefins) possessing various sensitive and/or reducible groups such as acetals, allylic alcohols, benzyl ethers, epoxides, esters, halides, nitriles, and sulfones is reported. The reduction is facile at 0 °C in aqueous N,N-dimethylacetamide containing sodium borohydride in the presence of 15 mol % ruthenium(III) chloride. Regioselective reduction of dienes is also feasible if the double bonds are sufficiently different in their structural environment.
Selective reduction of dienes/polyenes using sodium borohydride/catalytic ruthenium(III) in various liquid amide aqueous mixtures
Babler, James H.,Ziemke, David W.,Hamer, Robert M.
, p. 1754 - 1757 (2013)
An efficient method to effect selective reduction of several structurally diverse dienes and an unsymmetrical triene is reported. The reduction is facile at 0 °C in a liquid amide aqueous solution containing sodium borohydride in the presence of 15 mol % ruthenium(III) chloride. The chemoselectivity of the reaction is controlled by proper choice of the liquid amide solvent.
