1035897-64-3Relevant academic research and scientific papers
Stereoselective synthesis of cis- and trans-3-fluoro-1-phenylcyclobutyl amine
Shao, Pengcheng P.,Ye, Feng
, p. 3554 - 3557 (2008/09/21)
A stereoselective approach to the synthesis of cis- and trans-3-fluoro-1-phenylcyclobutylamine has been developed. Excellent stereoselectivity was obtained by the reduction of the appropriately substituted cyclobutanone to give either cis- or trans-isomers of 3-hydroxyl-1-phenylcyclobutylamine, which was stereoselectively converted to the 3-fluoro derivative.
