103597-45-1

Basic information

• Product Name: Ultraviolet Absorbent UV-360
• Synonyms: 2,2'-Methylenebis[2-hydroxy-5-(1,1,3,3-tetramethylbutyl)-1,3-phenylene]bis(2H-benzotriazole);2,2'-Methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2H-benzotriazol-2-yl)phenol];2,2'-Methylenebis[4-tert-octyl-6-(2H-benzotriazole-2-yl)phenol];Methylene bisbenzotriazoryl tetramethylbutyl phenol;Bisoctrizole (200 mg);2,2'-Methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetamethylbuty)phenol];2,2-Methylenebis[3-(2H-benzotriazol-2-yl)-5-(1,1,3,3-tetramethylbutyl)phenol],99%;UV Absorber 360
• CAS NO: 103597-45-1
• Molecular Formula: C₄₁H₅₀N₆O₂
• Molecular Weight: 658.87
• EINECS: 403-800-1
• Product Categories: Polymer Additives;Polymer Science;Stabilizers;AZILECT;Phenoles and thiophenoles
• Mol File: 103597-45-1.mol
• Article Data: 21

Chemical Properties

• Melting Point: 197-199 °C(lit.)
• Boiling Point: 771.6 °C at 760 mmHg
• Flash Point: >200°C
• Appearance: /
• Density: d20 1.2
• Vapor Pressure: 1.13E-24mmHg at 25°C
• Refractive Index: 1.615
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: almost transparency in THF
• PKA: 7.62±0.50(Predicted)
• Water Solubility: Insoluble < 5 ng/L at 25 °C
• Merck: 14,1294
• BRN: 11326835
• CAS DataBase Reference: Ultraviolet Absorbent UV-360(CAS DataBase Reference)
• NIST Chemistry Reference: Ultraviolet Absorbent UV-360(103597-45-1)
• EPA Substance Registry System: Ultraviolet Absorbent UV-360(103597-45-1)

Safety Data

• Statements: 36/37/38-53
• Safety Statements: 26-36/37/39-61
• WGK Germany: 1
• Hazardous Substances Data: 103597-45-1(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Bisoctrizole is a light stabilizer in polymers and resins. It is majorly used as a UV filter in sunscreens and in photo-luminescent dyes for organic electronic based applications.

Definition

ChEBI: Bisoctrizole is a diarylmethane. It is a broad-spectrum organic UV filter that is marketed as Tinosorb M. It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays.

General Description

Bisoctrizole is a benzotriazole based additive that is used as an ultraviolet absorber (UVA). It reduces degradation of the polymeric material by absorbing the UV radiation and converting it to thermal heat. Bisoctrizole is often added to sunscreen formulations that It may protect skin against blue light and other environmental assaults.

InChI:InChI=1/C41H50N6O2/c1-38(2,3)24-40(7,8)28-20-26(36(48)34(22-28)46-42-30-15-11-12-16-31(30)43-46)19-27-21-29(41(9,10)25-39(4,5)6)23-35(37(27)49)47-44-32-17-13-14-18-33(32)45-47/h11-18,20-23,48-49H,19,24-25H2,1-10H3

Upstream product

• 10333-53-6 bis-(dipropylamino)methane 
• 3147-75-9 Cyasorb UV 5411 
• 50-00-0 formaldehyd 

Relevant articles and documents

Solvent-free phase-transfer-catalysis synthesis of 2,2'-methylene-bis[4-tert-octyl-6-(2H-benzotriazolyl-2)]phenol

The invention relates to a method for synthesizing 2,2'-methylene-bis[4-tert-octyl-6-(2H-benzotriazolyl-2)]phenol (UV-360) through solvent-free phase transfer catalysis. The method comprises the procedures: adding UV-329, powdered sodium hydroxide, bis(di-n-propylamino)methane and a small amount of phase transfer catalyst into a reaction bulb which is equipped with a stirrer, a thermometer and a distillate receiving device, heating the reaction bulb to the temperature of about 120 DEG C with stirring, carrying out a reaction for 2 to 3 hours at this temperature and vacuum (100mmHg), and meanwhile, carrying out distilling-off so as to produce di-n-propyl amine; and after the reaction ends, carrying out procedures, such as toluene extraction, hydrochloric acid neutralization, crystallization and filtration, thereby obtaining the product. The synthesis method has the advantages that the reaction temperature is low, the reaction time is short, the yield and quality of the product are high, di-n-propyl amine is easy to recover, and the like.

Method for preparation of 2,2'-methylenebis[6-(2H-benzotriazole-2-yl)-4-(1,1,3,3-tetramethyl butyl)phenol]

The invention discloses a method for preparation of 2,2'-methylenebis[6-(2H-benzotriazole-2-yl)-4-(1,1,3,3-tetramethyl butyl)phenol]. The method comprises the steps: adding 2-(2-hydroxy-5-t-octyl)phenyl benzotriazole, an aromatic hydrocarbon solvent, secondary amine and paraformaldehyde into a reactor, heating up to 130-160 DEG C, carrying out a heat preservation dehydration reaction for 1-4 hours, adding a catalyst, dehydrating and heating up to 160-190 DEG C while heating, and carrying out heat preservation for 2-5 hours; and after the completion of the reaction, cooling the reaction liquid, neutralizing, carrying out alcohol precipitation, filtering, and drying to obtain UV-360. Compared with a conventional synthetic route, the yield of the product can reach more than or equal to 92%, and the maximum yield can reach more than or equal to 96%, so the production cost of the product is lower; the product has good quality, and the content of the product can reach more than or equal to 99.5%. Moreover, the operation process is simple and reliable, and the conditions are easy to control, so the method can meet demand of industrialized mass production.

ALPHA-AMINO ACID DERIVATIVES FOR IMPROVING SOLUBILITY

The invention relates to the use of α-amino acid derivatives for improving the solubility of poorly soluble substances in water or aqueous solutions and to mixtures and preferred preparations.