1036-14-2Relevant articles and documents
Synthesis of a series of new platinum organometallic complexes derived from bidentate Schiff-base ligands and their catalytic activity in the hydrosilylation and dehydrosilylation of styrene
Lachachi, M. Belhadj,Benabdallah, Tayeb,Aguiar, Pedro M.,Youcef, M. Hadj,Whitwood, Adrian C.,Lynam, Jason M.
, p. 11919 - 11928 (2015)
The synthesis and properties of a novel class of platinum complexes containing Schiff bases as O,N-bidentate ligands is described as are the solution and solid state properties of the uncomplexed ligands. The platinum complexes were prepared from [PtBr2(COD)] (COD = 1,5-cyclooctadiene) and N-(2-hydroxy-1-naphthalidene)aniline derivatives in the presence of base (NaOBut). Instead of a substitution reaction to afford cationic species, the addition of the Schiff base ligands results in both the formal loss of two equivalents of bromide and addition of hydroxide to the COD ligand of the complexes. It is proposed that this reaction proceeds through a cationic platinum complex [Pt(N-O)(COD)]Br which then undergoes addition of water and loss of HBr. An example of a dinuclear platinum complex in which two cyclo-octene ligands are bridged by an ether linkage is also reported. The platinum complexes were evaluated as catalysts for the hydrogenative and dehydrogenative silylation of styrene, the resulting behaviour is substituent, time and temperature dependent.
The structures of the adducts formed from organotin moieties and 1--2-naphthol. Crystal structure of chloro-trimethyl-2-naphthol>tin(IV): Me3SnCl*
Teoh, Siang-Guan,Teo, Soon-Beng,Yeap, Guan-Yeow,Fun, Hoong-Kun,Smith, Peter J.
, p. 73 - 77 (1993)
A series of adducts resulting from the coordinative interaction of RSnCl3, R2SnCl2 and R3SnCl (R = Me and Ph) with 1--2-naphthol have been made.An X-ray crystal structural study of the trimethyltin(IV) derivative has ben carr
Synthesis, spectroscopic characterization, catalytic and antibacterial studies of ruthenium(III) Schiff base complexes
Shoair,El-Shobaky,Abo-Yassin
, p. 217 - 227 (2015)
The bidentate Schiff base ligands (HLn) have been synthesized by condensation of 2-hydroxy-l-naphthaldehyde with aniline and its p-substituted derivatives in ethanol. Ruthenium(III) complexes of the type [Ru(Ln)2(H2O)2]Cl have been synthesized by the reaction of RuCl3·nH2O with the Schiff base ligands (in a molar ratio 1:2) in ethanol. The ligands and their Ru(III) complexes have been characterized by elemental analysis, magnetic susceptibility, spectroscopic (FTIR, UV-vis, 1H NMR and X-ray diffraction) and thermal analysis techniques. All the ruthenium(III) complexes are found to be stable, paramagnetic, low spin and octahedrally coordinated by the ligands through the nitrogen atom of the azomethine (-CN-) group and the oxygen atom of the deprotonated phenolic group. The molecular and electronic structures of the investigated ligands (HLn) were also studied using quantum chemical calculations. The complexes (1, 3 and 5) exhibited a catalytic activity for the oxidation of benzoin to benzil with moderate to high yield in the presence of sodium periodate as co-oxidant. The antibacterial activities of the ligands (HLn) and their Ru(III) complexes towards Gram positive and Gram negative bacteria have been investigated.
Synthesis, structure-activity relationships and preliminary mechanism study of N-benzylideneaniline derivatives as potential TLR2 inhibitors
Cai, Shaoyi,Zhu, Gengzheng,Cen, Xiaohong,Bi, Jingjie,Zhang, Jingru,Tang, Xiaoshan,Chen, Kun,Cheng, Kui
, p. 2041 - 2050 (2018/03/13)
Toll-like receptor 2 (TLR2) can recognize pathogen-associated molecular patterns to defense against invading organisms and has been represents an attractive therapeutic target. Until today, none TLR2 small molecule antagonist have been developed in clinic
N,O-coordinated bivalent nickel complex with binaphthol structure and preparation method thereof
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Paragraph 0027; 0028; 0029, (2017/08/29)
The invention provides N,O-coordinated bivalent nickel complex with binaphthol structure, having a structural formula shown in the description; the invention also provides a preparation method of the N,O-coordinated bivalent nickel complex with binaphthol
A General and Practicable Synthesis of Polycyclic Heteroaromatic Compounds. Part 4. A Rationale for the Mechanism of the Synthesis
Asherson, Janet L.,Bilgic, Orhan,Young, Douglas W.
, p. 3041 - 3047 (2007/10/02)
Studies on aspects of the mechanism of our general synthesis of polycyclic heteroaromatic compounds suggest that the reaction sequence outlined in Scheme 2 is followed.Under the conditions of our synthesis, the ortho-rearrangement (8) --> (9) is preferred to the para-rearrangement which is known to occur in acid conditions.Aniline Mannich bases (29) are converted to benzacridines (30) in an intermolecular reaction.The synthesis appears to be restricted to substrates where the putative intermediate (9) is not part of an amide group.In the course of these studies effective syntheses of the tricyclic compounds (24) and (25) have been discovered.
