1036243-86-3

Basic information

• Product Name: N-(2-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetamide
• Synonyms: N-(2-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetamide
• CAS NO: 1036243-86-3
• Molecular Weight: 252.275
• Mol File: 1036243-86-3.mol
• Article Data: 2

Chemical Properties

• Density: 1.351±0.06 g/cm3(Predicted)
• CAS DataBase Reference: N-(2-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetamide(1036243-86-3)
• EPA Substance Registry System: N-(2-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetamide(1036243-86-3)

Safety Data

• Hazardous Substances Data: 1036243-86-3(Hazardous Substances Data)

Upstream product

• 169760-16-1 2-acetamidophenylboronic acid 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 1036243-39-6 2-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzenamine 

Relevant articles and documents

A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors

Pictet-Spengler condensation of aldehydes or alpha-keto-esters with 4-(2-anilinophenyl)-7-azaindole (11) or deazapurine (12) gave high yields of the 3,4-fused cyclic compounds. SAR studies, by varying the substituted benzaldehyde components, lead to the discovery of a series of potent JAK2 kinase inhibitors.