1036298-14-2

Basic information

• Product Name: ethyl 2-methoxy-4-((1E)-3-oxo-3-{[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]amino}prop-1-enyl)phenyl carbonate
• Synonyms: ethyl 2-methoxy-4-((1E)-3-oxo-3-{[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]amino}prop-1-enyl)phenyl carbonate
• CAS NO: 1036298-14-2
• Molecular Weight: 517.625
• Mol File: 1036298-14-2.mol

Chemical Properties

• CAS DataBase Reference: ethyl 2-methoxy-4-((1E)-3-oxo-3-{[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]amino}prop-1-enyl)phenyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-methoxy-4-((1E)-3-oxo-3-{[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]amino}prop-1-enyl)phenyl carbonate(1036298-14-2)
• EPA Substance Registry System: ethyl 2-methoxy-4-((1E)-3-oxo-3-{[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]amino}prop-1-enyl)phenyl carbonate(1036298-14-2)

Safety Data

• Hazardous Substances Data: 1036298-14-2(Hazardous Substances Data)

Upstream product

• 42381-67-9 (2E)-3-{4-[(ethoxycarbonyl)oxy]-3-methoxyphenyl}acrylic acid 
• 249290-07-1 9-(4-aminobutylamino)-1,2,3,4-tetrahydroacridine 

Downstream Products

• 1036298-19-7 C₂₇H₃₁N₃O₃ 

Relevant articles and documents

Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates

Five tacrine-ferulic acid hybrids (6a-e) were designed and synthesized as multi-potent anti-Alzheimer drug candidates. All target compounds have better acetylcholinesterase inhibitory activity and comparable butyrylcholinesterase inhibitory activity in relation to tacrine. Interestingly, 6d showed a reversible and non-competitive inhibitory action for acetylcholinesterase indicating interaction with the peripheral anionic site, whereas a reversible but competitive inhibitory action for butyrylcholinesterase. The antioxidant study revealed that four target compounds have, compared to Trolox, high ability to absorb reactive oxygen species.