1036334-47-0

Basic information

• Product Name: C₁₆H₂₀N₂O₂
• CAS NO: 1036334-47-0
• Molecular Weight: 272.347
• Mol File: 1036334-47-0.mol

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₀N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₀N₂O₂(1036334-47-0)
• EPA Substance Registry System: C₁₆H₂₀N₂O₂(1036334-47-0)

Safety Data

• Hazardous Substances Data: 1036334-47-0(Hazardous Substances Data)

Relevant articles and documents

Pyridyl-phenyl ether monoamine reuptake inhibitors: Impact of lipophilicity on dual SNRI pharmacology and off-target promiscuity

A novel series of pyridyl-phenyl ethers are disclosed, which possess dual 5-HT and NA reuptake pharmacology with good selectivity over dopamine reuptake inhibition. An analysis of the relationship between lipophilicity and pharmacology highlighted that potent dual SNRI activity was only achievable at c log P > 3.5. The series was found to possess significant polypharmacology issues, and we concluded that this off-target promiscuity was related to lipophilicity.