1036380-75-2

Basic information

• Product Name: Methyl 3-aMino-5-broMobenzo[b]thiophene-2-carboxylate
• Synonyms: Methyl 3-aMino-5-broMobenzo[b]thiophene-2-carboxylate;3-AMino-5-broMo-benzo[b]thiophene-2-carboxylic acid Methyl ester;ethyl 3-aMino-5-broMobenzo[b]thiophene-2-carboxylate
• CAS NO: 1036380-75-2
• Molecular Formula: C₁₀H₈BrNO₂S
• Molecular Weight: 286.14502
• Mol File: 1036380-75-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 414.6±40.0 °C(Predicted)
• Appearance: /
• Density: 1.689±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -0.01±0.10(Predicted)
• CAS DataBase Reference: Methyl 3-aMino-5-broMobenzo[b]thiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-aMino-5-broMobenzo[b]thiophene-2-carboxylate(1036380-75-2)
• EPA Substance Registry System: Methyl 3-aMino-5-broMobenzo[b]thiophene-2-carboxylate(1036380-75-2)

Safety Data

• Hazardous Substances Data: 1036380-75-2(Hazardous Substances Data)

Usage

General Description

Methyl 3-amino-5-bromobenzo[b]thiophene-2-carboxylate is a chemical compound with the formula C??H??BrNO?S. It is a derivative of benzo[b]thiophene, a heterocyclic compound containing a thiophene ring fused to a benzene ring. The presence of the amino and ester functional groups makes this compound useful in the synthesis of pharmaceuticals and agrochemicals. It is also known for its potential biological activities and is used as a building block in organic chemistry. The bromine substituent on the benzene ring is important for controlling the reactivity and selectivity of chemical reactions. Methyl 3-amino-5-bromobenzo[b]thiophene-2-carboxylate is a versatile compound with potential applications in various industries including pharmaceutical, agrochemical, and organic synthesis.

Upstream product

• 61272-71-7 3-amino-5-bromo-1H-indazole 
• 2365-48-2 Methyl thioglycolate 
• 179897-89-3 5-Bromo-2-fluoro-benzonitrile 

Downstream Products

• 45859-82-3 5-bromobenzo[b]thiophen-3-amine 

Relevant articles and documents

Cu-Catalyzed Denitrogenative Transannulation of 3-Aminoindazoles to Assemble 1-Aminoisoquinolines and 3-Aminobenzothiophenes

We disclose a novel Cu-catalyzed denitrogenative transannulation of 3-aminoindazoles to afford diverse functionalized 3-aminobenzothiophenes and 1-aminoisoquinolines, in which denitrogenative transannulation of 3-aminoindazoles is reported for the first t

BENZENE FUSED HETEROCYCLIC COMPOUND AND USE THEREOF

The present disclosure provides a benzene fused heterocyclic compound of Formula (I): wherein (A) is a single or double bond; n is 0 or 1; X is -CH2-, O, NR1, or S; A is -C(Ra1)(Ra2)(Ra3) or -N(R

Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors

Microwave irradiation of 2-halobenzonitriles and methyl thioglycolate in the presence of triethylamine in DMSO at 130°C provides rapid access to 3-aminobenzo[b]thiophenes in 58-96% yield. This transformation has been applied in the synthesis of the thieno