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1036402-20-6

(R)-2'-{1-chloro-(S)-8-[2-(2,5-difluoro-4-trifluoromethylphenyl)ethyl]-3-ethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl}-N-methyl-2'-phenylacetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (R)-2'-{1-chloro-(S)-8-[2-(2,5-difluoro-4-trifluoromethylphenyl)ethyl]-3-ethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl}-N-methyl-2'-phenylacetamide

    Cas No: 1036402-20-6

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  • 1036402-20-6 Structure

  • Basic information

    1. Product Name: (R)-2'-{1-chloro-(S)-8-[2-(2,5-difluoro-4-trifluoromethylphenyl)ethyl]-3-ethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl}-N-methyl-2'-phenylacetamide
    2. Synonyms:
    3. CAS NO:1036402-20-6
    4. Molecular Formula:
    5. Molecular Weight: 540.964
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1036402-20-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-2'-{1-chloro-(S)-8-[2-(2,5-difluoro-4-trifluoromethylphenyl)ethyl]-3-ethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl}-N-methyl-2'-phenylacetamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-2'-{1-chloro-(S)-8-[2-(2,5-difluoro-4-trifluoromethylphenyl)ethyl]-3-ethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl}-N-methyl-2'-phenylacetamide(1036402-20-6)
    11. EPA Substance Registry System: (R)-2'-{1-chloro-(S)-8-[2-(2,5-difluoro-4-trifluoromethylphenyl)ethyl]-3-ethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl}-N-methyl-2'-phenylacetamide(1036402-20-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1036402-20-6(Hazardous Substances Data)

1036402-20-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1036402-20-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,6,4,0 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1036402-20:
(9*1)+(8*0)+(7*3)+(6*6)+(5*4)+(4*0)+(3*2)+(2*2)+(1*0)=96
96 % 10 = 6
So 1036402-20-6 is a valid CAS Registry Number.

1036402-20-6Downstream Products

1036402-20-6Relevant articles and documents

Structure-activity relationship studies and sleep-promoting activity of novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 2

Sifferlen, Thierry,Koberstein, Ralf,Cottreel, Emmanuelle,Boller, Amandine,Weller, Thomas,Gatfield, John,Brisbare-Roch, Catherine,Jenck, Francois,Boss, Christoph

, p. 3857 - 3863 (2013/07/27)

Replacement of the dimethoxyphenyl moiety in the core skeleton of almorexant by appropriately substituted imidazoles afforded novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as potent dual orexin receptor antagonists. We describe in th

5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES

-

Page/Page column 136-137, (2008/12/06)

The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I),wherein X represents CH2 or O; R1 represents a phenyl group, which group is independently mono-, di-, or tri-substituted wherein the substituents are independently selected from the group consisting of (C1-4)alkyl, (C1-4)alkoxy, halogen, cyano, trifluoromethoxy and trifluoromethyl; R2 represents (C1-4)alkyl, (C1-4)alkoxy, (C2-4)alkenyl, halogen, cyano, hydroxymethyl, trifluoromethyl, C(O)NR5R6 or cyclopropyl; R3 represents (C1-4)alkyl, (C1-4)alkoxy-methyl or halogen; R4 represents (C1-4)alkyl; R5 represents hydrogen or (C1-4)alkyl; and R6 represents hydrogen or (C1-4)alkyl. The invention also relates to pharmaceutically acceptable salts of such compounds; and to the use of such compounds as medicaments; especially as orexin receptor antagonists.

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