1036478-85-9

Basic information

• Product Name: N-(4-methoxyphenyl)-N-[1-(4-methylphenyl)propyl]amine
• Synonyms: N-(4-methoxyphenyl)-N-[1-(4-methylphenyl)propyl]amine
• CAS NO: 1036478-85-9
• Molecular Weight: 255.36
• Mol File: 1036478-85-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(4-methoxyphenyl)-N-[1-(4-methylphenyl)propyl]amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)-N-[1-(4-methylphenyl)propyl]amine(1036478-85-9)
• EPA Substance Registry System: N-(4-methoxyphenyl)-N-[1-(4-methylphenyl)propyl]amine(1036478-85-9)

Safety Data

• Hazardous Substances Data: 1036478-85-9(Hazardous Substances Data)

Upstream product

• 1073339-65-7 C₁₇H₁₉NO 
• 104-94-9 4-methoxy-aniline 
• 5337-93-9 4'-methylpropiophenone 
• 97-94-9 triethyl borane 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 1073339-58-8 (S)-4-methoxy-N-(1-p-tolylpropyl)aniline 

Relevant articles and documents

Cooperative Mn(i)-complex catalyzed transfer hydrogenation of ketones and imines

The synthesis and reactivity of Mn(i) complexes bearing bifunctional ligands comprising both the amine N-H and benzimidazole fragments are reported. Among the various ligands, the N-((1H-benzimidazol-2-yl)methyl)aniline ligand containing Mn(i) complex presented higher reactivity in the transfer hydrogenation (TH) of ketones in 2-propanol. Experimentally, it was established that both the benzimidazole and amine N-H proton played a vital role in the enhancement of the catalytic activity. Utilizing this system a wide range of aldehydes and ketones were reduced efficiently. Notably, the TH of several imines, as well as chemoselective reduction of unsaturated ketones, was achieved in the presence of this catalyst. DFT calculations were carried out to understand the plausible reaction mechanism which disclosed that the transfer hydrogenation reaction followed a concerted outer-sphere mechanism.

Iron-catalyzed transfer hydrogenation of imines assisted by an iron-based Lewis acid

An iron-catalyzed transfer hydrogenation of N-aryl and N-alkyl imines using isopropanol as the hydrogen donor is reported for the first time. A combination of two iron complexes serving different roles is the key for the success of this catalytic system. As a result, an environmentally friendly and precious metal-free transfer hydrogenation of imines has been developed. The use of a suitable co-catalyst as an activator not only led to efficient transfer hydrogenation, but also showed potential in enantioselective transformation.