103660-49-7Relevant articles and documents
SYNTHESIS, STRUCTURE, AND PROPERTIES OF PYRAZOLOQUINUCLIDINE DERIVATIVES
Turchin, K. F.,Yanina, A. D.,Filipenko, T. Ya.,Mikhlina, E. E.,Sheinker, Yu. N.,Yakhtonov, L. N.
, p. 1039 - 1048 (2007/10/02)
It was shown by means of 1H and 13C NMR spectroscopy that the reaction of 2-arylmethylene-3-oxoquinuclidines with hydrazine hydrate gives 4a-hydroxy-7-aryl-4a,5,7,7a-tetrahydropyrazoloquinuclidines, which are stable in the crystalline state but undergo dehydration to the corresponding 7-aryl-6H-7,7a-dihydropyrazoloquinuclidines in solutions.The latter undergo cleavage to the 3-(4-piperidyl)-5-arylpyrazoles when they are heated in an alkaline medium.
