Welcome to LookChem.com Sign In|Join Free

CAS

  • or
(2S)-2-(5-benzoylthiophen-2-yl)propanoic acid is a chemical compound with a molecular formula of C16H14O3S. It is a yellow crystalline powder that is insoluble in water but soluble in organic solvents. (2S)-2-(5-benzoylthiophen-2-yl)propanoic acid is a derivative of 2-thiopheneacetic acid and is known for its potential anti-inflammatory and analgesic properties.

103667-50-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 103667-50-1 Structure
  • Basic information

    1. Product Name: (2S)-2-(5-benzoylthiophen-2-yl)propanoic acid
    2. Synonyms:
    3. CAS NO:103667-50-1
    4. Molecular Formula: C14H12O3S
    5. Molecular Weight: 260.3083
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 103667-50-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 450.3°C at 760 mmHg
    3. Flash Point: 226.1°C
    4. Appearance: N/A
    5. Density: 1.29g/cm3
    6. Vapor Pressure: 6.8E-09mmHg at 25°C
    7. Refractive Index: 1.612
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: (2S)-2-(5-benzoylthiophen-2-yl)propanoic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: (2S)-2-(5-benzoylthiophen-2-yl)propanoic acid(103667-50-1)
    12. EPA Substance Registry System: (2S)-2-(5-benzoylthiophen-2-yl)propanoic acid(103667-50-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 103667-50-1(Hazardous Substances Data)

103667-50-1 Usage

Uses

Used in Pharmaceutical Industry:
(2S)-2-(5-benzoylthiophen-2-yl)propanoic acid is used as an intermediate in the synthesis of various pharmaceuticals for its potential anti-inflammatory and analgesic properties. It aids in the development of new drugs for pain management and inflammation.
Used in Agrochemical Industry:
(2S)-2-(5-benzoylthiophen-2-yl)propanoic acid is used as a building block in the synthesis of agrochemicals, contributing to the development of effective products for agricultural applications.
Used in Organic Synthesis:
(2S)-2-(5-benzoylthiophen-2-yl)propanoic acid is used as a key component in the synthesis of other organic compounds and materials, thanks to the benzoyl group present in its molecule. This makes it a valuable asset in the field of organic chemistry for creating a variety of new substances with diverse applications.

Check Digit Verification of cas no

The CAS Registry Mumber 103667-50-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,6,6 and 7 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 103667-50:
(8*1)+(7*0)+(6*3)+(5*6)+(4*6)+(3*7)+(2*5)+(1*0)=111
111 % 10 = 1
So 103667-50-1 is a valid CAS Registry Number.

103667-50-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-(5-benzoylthiophen-2-yl)propanoic acid

1.2 Other means of identification

Product number -
Other names R-tiaprofenic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103667-50-1 SDS

103667-50-1Downstream Products

103667-50-1Relevant articles and documents

Synthesis of α-heteroarylpropanoic acid via asymmetric hydroformylation catalyzed by Rh(I)-(R,S)-BINAPHOS and the subsequent oxidation

Tanaka, Ryo,Nakano, Koji,Nozaki, Kyoko

, p. 8671 - 8676 (2008/03/12)

(Chemical Equation Presented) The asymmetric hydroformylation of vinyl heteroarenes (vinylfurans and vinylthiophenes) was investigated by using Rh(I)-BINAPHOS derivatives as a catalyst. The hydroformylation of vinylthiophenes 1 gave the corresponding branched aldehydes 2 with high enantiopurities as major products. Oxidation of the aldehydes 2 successfully afforded α-heteroarylpropanoic acids 4 in good yields. In addition, the aldehydes 2 were reduced to alcohols 5 without loss of enantiomeric excess.

Enzymatic enantioselective ester hydrolysis by carboxylesterase NP

Smeets, J. W. H.,Kieboom, A. P. G.

, p. 490 - 495 (2007/10/02)

The enzymatic hydrolysis of a series of carboxylic esters by carboxylesterase NP has been investigated in order to determine the scope and limitations of this enzyme. 2-Substituted propionates were hydrolyzed with high enantioselectivity when an aromatic moiety was part of the 2-substituent.Enantioselective hydrolysis could be accomplished with several 2-arypropionates, 2-(aryloxy)propionates and N-arylalanine esters.The propionate esters yielded propionic acids as (S) enantiomers, whereas the alanine esters yielded the (R) enantiomers.Without a 2-aryl substituent, the enzymatic hydrolysis of the propionates occurred at a lower rate without acceptable enantioselectivity.In addition to 2-substituted propionates, only a few other esters were hydrolyzed with high enantioselectivity by carboxylesterase NP, such as some prochiral disubstituted malonates. 1-Phenylethylacetate was the only substrate with chirality in the alcohol part of the ester that was found to be hydrolyzed enantioselectively.Carboxylesterase NP proved to be a powerful enzyme for kinetic resolution of propionate esters with an aromatic ring containing a 2-substituent.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 103667-50-1