1036734-41-4Relevant academic research and scientific papers
Hindered diarylether and diarylsulfone bisphosphine ligands: Atropisomerism and palladium complexes
Clayden, Jonathan,Fletcher, Stephen P.,Senior, James,Worrall, Christopher P.
scheme or table, p. 1355 - 1360 (2010/10/21)
Phosphines and bisphosphines derived from hindered ortho-substituted diaryl ethers and diarylsulfones by lithiation are, with appropriate substitution patterns, resolvable atropisomeric ligands which form crystalline complexes with palladium dichloride.
Enantioselective synthesis of an atropisomeric diaryl ether
Clayden, Jonathan,Worrall, Christopher P.,Moran, Wesley J.,Helliwell, Madeleine
supporting information; experimental part, p. 3234 - 3237 (2009/02/08)
(Chemical Equation Presented) Twisted ethers: Introduction of a bulky alkylsulfinyl substituent ortho to the C-O axis of a diaryl ether imposes a powerful conformational preference (see scheme). The preference persists upon oxidation of the sulfoxide to a sulfone, leading to dynamic thermodynamic resolution of the atropisomeric ether. This is the first enantioselective synthesis of an atropisomeric diaryl ether not forming part of a macrocyclic ring.
