1036736-85-2

Basic information

• Product Name: 4-{[6-(6-fluoro-pyridin-3-yl)-4-(2,2,2-trifluoro-ethylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide
• CAS NO: 1036736-85-2
• Molecular Weight: 507.471
• Mol File: 1036736-85-2.mol

Chemical Properties

• CAS DataBase Reference: 4-{[6-(6-fluoro-pyridin-3-yl)-4-(2,2,2-trifluoro-ethylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[6-(6-fluoro-pyridin-3-yl)-4-(2,2,2-trifluoro-ethylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide(1036736-85-2)
• EPA Substance Registry System: 4-{[6-(6-fluoro-pyridin-3-yl)-4-(2,2,2-trifluoro-ethylamino)-pyrido[3,2-d]pyrimidin-2-ylamino]-methyl}-benzenesulfonamide(1036736-85-2)

Safety Data

• Hazardous Substances Data: 1036736-85-2(Hazardous Substances Data)

Upstream product

• 175358-01-7 3-amino-6-chloro-pyridine-2-carboxylic acid amide 
• 1036738-25-6 4-((6-chloro-4-(2,2,2-trifluoroethylamino)pyrido[3,2-d]pyrimidin-2-ylamino)methyl)benzenesulfonamide 
• 351019-18-6 (6-fluoropyridin-3-yl)boronic acid 
• 1203655-68-8 2,6-dichloro-N-(2,2,2-trifluoroethyl)pyrido[3,2-d]pyrimidin-4-amine 
• 1036738-12-1 2,4,6-trichloropyrido[3,2-d]pyrimidine 
• 897360-38-2 6-chloropyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

Optimization of pharmacokinetics through manipulation of physicochemical properties in a series of HCV inhibitors

A novel series of HCV replication inhibitors based on a pyrido[3,2-d]pyrimidine core were optimized for pharmacokinetics (PK) in rats. Several associations between physicochemical properties and PK were identified and exploited to guide the design of comp

PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS

Pyrido(3,2-d)pyrimidine derivatives represented by the structural formula (I), wherein: R4 is hydrogen, and R1, R2 and R3 together provide a specific substitution pattern, pharmaceutical acceptable addition salt