1036738-82-5 Usage
Uses
Used in Pharmaceutical Industry:
1-(Cyclopropylsulfonyl)-4-piperidinecarbonitrile is used as an intermediate in the synthesis of pharmaceutical compounds for its ability to be incorporated into the structure of potent and selective inhibitors of protein kinases. These inhibitors play a crucial role in the development of drugs targeting various diseases.
Used in Cancer Treatment:
In the field of oncology, 1-(Cyclopropylsulfonyl)-4-piperidinecarbonitrile is used as a building block for the development of drugs that target protein kinases involved in cancer cell growth and proliferation. Its incorporation into pharmaceutical compounds can potentially lead to the creation of effective treatments for various types of cancer.
Used in Inflammatory Disorders Treatment:
1-(Cyclopropylsulfonyl)-4-piperidinecarbonitrile is utilized as a component in the synthesis of drugs that address inflammatory disorders. By targeting specific protein kinases, these drugs can help regulate immune responses and reduce inflammation, providing relief for patients suffering from such conditions.
Used in Neurodegenerative Disease Treatment:
1-(Cyclopropylsulfonyl)-4-piperidinecarbonitrile is also used in the development of pharmaceuticals for the treatment of neurodegenerative diseases. Its role as a building block for protein kinase inhibitors can contribute to the creation of drugs that slow down or halt the progression of these debilitating conditions, offering hope for patients and their caregivers.
Check Digit Verification of cas no
The CAS Registry Mumber 1036738-82-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,6,7,3 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1036738-82:
(9*1)+(8*0)+(7*3)+(6*6)+(5*7)+(4*3)+(3*8)+(2*8)+(1*2)=155
155 % 10 = 5
So 1036738-82-5 is a valid CAS Registry Number.
1036738-82-5Relevant articles and documents
PROCESS FOR PREPARING CCR-5 RECEPTOR ANTAGONISTS UTILIZING 4-SUBSTITUTED 1-CYCLOPROPANE-SULFONYL-PIPERIDINYL COMPOUNDS
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Page/Page column 35-36, (2008/12/07)
The present invention discloses a novel process to prepare 4-substituted 1-Cyclopropane-sulfonyl-Piperidinyl compounds, which are useful intermediates for the preparation of antagonists of CCR5 receptor and therefore useful for the treatment of HIV virus infected mammals. It specifically discloses a novel process to synthesize 4-[4-[(R)-[1-[cyclopropylsulfonyl)-4-piperidinyl](3-fluorophenyl)methyl]-3(S)-methyl-1-piperazinyl]-1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-methylpiperidine] compounds.