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2-Amino-5-bromo-4-chloro-benzaldehyde is a chemical compound with the systematic name 2-amino-5-bromo-4-chlorobenzaldehyde. It is a benzaldehyde derivative featuring an amino group and halogen substituents, specifically bromo and chloro, attached to the benzene ring. 2-Amino-5-bromo-4-chloro-benzaldehyde is recognized for its versatile reactivity and functional groups, making it a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its potential biological activities and role in molecular and medicinal chemistry are also of interest.

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  • 1036757-11-5 Structure
  • Basic information

    1. Product Name: 2-Amino-5-bromo-4-chloro-benzaldehyde
    2. Synonyms: 2-Amino-5-bromo-4-chloro-benzaldehyde;Benzaldehyde, 2-amino-5-bromo-4-chloro-
    3. CAS NO:1036757-11-5
    4. Molecular Formula: C7H5BrClNO
    5. Molecular Weight: 234.4777
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1036757-11-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Amino-5-bromo-4-chloro-benzaldehyde(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Amino-5-bromo-4-chloro-benzaldehyde(1036757-11-5)
    11. EPA Substance Registry System: 2-Amino-5-bromo-4-chloro-benzaldehyde(1036757-11-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1036757-11-5(Hazardous Substances Data)

1036757-11-5 Usage

Uses

Used in Pharmaceutical Synthesis:
2-Amino-5-bromo-4-chloro-benzaldehyde is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be readily modified and incorporated into complex molecular structures. Its presence in drug molecules can contribute to desired pharmacological properties, such as improved potency, selectivity, or bioavailability.
Used in Agrochemical Production:
In the agrochemical industry, 2-Amino-5-bromo-4-chloro-benzaldehyde serves as a crucial building block for the development of new pesticides or herbicides. Its unique combination of functional groups allows for the creation of compounds with specific modes of action, potentially leading to more effective and targeted agricultural products.
Used in Organic Chemistry Research:
2-Amino-5-bromo-4-chloro-benzaldehyde is utilized as a versatile compound in organic chemistry research for exploring novel reactions and synthetic pathways. Its reactivity and the presence of multiple functional groups make it an ideal candidate for studying new methods in organic synthesis and for the development of innovative synthetic strategies.
Used in Molecular and Medicinal Chemistry:
2-Amino-5-bromo-4-chloro-benzaldehyde is also studied for its potential biological activities, which can be harnessed in molecular and medicinal chemistry. Its unique structure may allow it to interact with biological targets in ways that could lead to the discovery of new therapeutic agents or probes for biological research.

Check Digit Verification of cas no

The CAS Registry Mumber 1036757-11-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,6,7,5 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1036757-11:
(9*1)+(8*0)+(7*3)+(6*6)+(5*7)+(4*5)+(3*7)+(2*1)+(1*1)=145
145 % 10 = 5
So 1036757-11-5 is a valid CAS Registry Number.

1036757-11-5Relevant articles and documents

Compound with AMPK agonistic activity and preparation and application of prodrug thereof

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Paragraph 0145; 0157-0158, (2021/10/27)

The invention relates to a compound with AMPK agonistic activity and a prodrug thereof, and as well as a preparation method and medical application of a prodrug thereof. The compound has the structure shown in the formula (I), and the prodrug of the compound has the structure shown in the formula (II), wherein each group and the substituent are as defined in the specification. The invention discloses a preparation method of the compound and application of the compound in prevention and treatment AMPK related diseases, and the AMPK related diseases include, but are not limited to, energy metabolism abnormality related diseases. Neurodegenerative diseases and inflammation-related diseases and the like.

INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR

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Paragraph 0407; 0412; 0413, (2015/05/05)

Described herein are inhibitors of FGFR-4, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.

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