103676-85-3Relevant academic research and scientific papers
Zn-Mediated Hydrodeoxygenation of Tertiary Alkyl Oxalates
Ye, Yang,Ma, Guobin,Yao, Ken,Gong, Hegui
supporting information, p. 1625 - 1628 (2021/01/18)
Herein we describe a general, mild, and scalable method for hydrodeoxygenation of readily accessible tertiary alkyl oxalates by Zn/silane under Ni-catalyzed conditions. The reduction method is suitable for an array of structural motifs derived from tertiary alcohols that bear diverse functional groups, including the synthesis of a key intermediate en route to estrone.
Blue light-promoted photolysis of aryldiazoacetates
Jurberg, Igor D.,Davies, Huw M. L.
, p. 5112 - 5118 (2018/06/12)
Aryldiazoacetates can undergo photolysis under blue light irradiation (460-490 nm) at room temperature and under air in the presence of numerous trapping agents, such as styrene, carboxylic acids, amines, alkanes and arenes, thus providing a straighforward and general platform for their mild functionalization.
Iron-Catalyzed Carbenoid Insertion into C(sp 3)-H Bonds
Cheng, Qing-Qing,Yang, Ji-Min,Xu, Huan,Zhu, Shou-Fei
supporting information, p. 1327 - 1330 (2017/06/27)
An iron-catalyzed carbenoid insertion into C-H bonds of alkanes was developed with high activity (turnover numbers up to 690 in a gram-scale experiment) and chemoselectivity. This non-heme iron-catalyzed C(sp 3)-H insertion reaction provides an efficient strategy for C-H functionalization.
Highly selective metal catalysts for intermolecular carbenoid insertion into primary C-H bonds and enantioselective C-C bond formation
Thu, Hung-Yat,Tong, Glenna So-Ming,Huang, Jie-Sheng,Chan, Sharon Lai-Fung,Deng, Qing-Hai,Che, Chi-Ming
scheme or table, p. 9747 - 9751 (2009/05/30)
(Figure Presented) Primary C-H bond activation! A Rh complex of bis-pocket porphyrin I catalyzes carbenoid insertion into the C-H bonds of n-alkanes with a primary/secondary selectivity (per C-H bond) of up to 11.4:1 (see picture). Enantioselective secondary C-H bond functionalization catalyzed by a Rh complex of Halterman's chiral porphyrin features up to 93% ee. These reactions exhibit up to 6477 turnovers after the catalyst was recycled five times.
