103702-18-7

Upstream product

• 22065-57-2 ethyl 2-phenyldiazoacetate 
• 150-76-5 4-methoxy-phenol 
• 611-71-2 MANDELIC ACID 

Downstream Products

• 1258326-22-5 C₂₅H₁₉NO₅ 
• 1314114-27-6 1-[(3R)-2,3-dihydro-5-methoxy-2-oxo-3-phenyl-3-benzofuranyl]-1,2-hydrazinedicarboxylic acid,1,2-bis(phenylmethyl) ester 
• 1374605-22-7 C₂₉H₂₄O₇S₂ 
• 118709-27-6 2-(2,3-dihydro-5-methoxy-2-oxo-3-phenylbenzofuran-3-yl)acetic acid 
• 14770-96-8 oxybenzone 
• 623163-90-6 5-methoxy-3-phenyl-3-(2-propenyl)-2(3H)benzofuranone 

Relevant academic research and scientific papers

Br?nsted acid-catalyzed Friedel-Crafts-type alkylation of arenes with α-aryl diazoacetates

An efficient Br?nsted acid-catalyzed Friedel-Crafts-type alkylation of arenes with α-aryl diazoacetates has been developed. This protocol enables effective access to various highly functionalized diarylmethane derivatives in moderate to high yields. Moreo

Nickel-Catalyzed Decarbonyloxidation of 3-Aryl Benzofuran-2(3H)-ones to 2-Hydroxybenzophenones

We have developed a protocol to facilitate the nickel-catalyzed decarbonyloxidation of 3-aryl benzofuran-2(3H)-ones to 2-hydroxybenzophenones under mild conditions, which is an efficient approach for the decarbonyloxidation of lactones in organic synthesis. A diverse range of substrates can undergo C(O)-O/C(O)-C bond cleavage to generate the target products in good yields. These 2-hydroxybenzophenones can be converted into a variety of compounds via reactions such as esterification, cyclization, and reduction.

A benzofuran compound and its efficient catalytic synthesis method

The invention discloses a to trifluoromethanesulfonic acid nickel as catalyst, in order to mandelic acid and phenol as raw materials, and efficient synthesis of the benzofuran compound of the method, this method has the advantages of low cost, high yield,

Recyclable nickel-catalyzed C-H/O-H dual functionalization of phenols with mandelic acids for the synthesis of 3-aryl benzofuran-2(3: H)-ones under solvent-free conditions

Herein, we developed a protocol for the efficient synthesis of 3-aryl benzofuran-2(3H)-ones under solvent-free conditions from phenols and mandelic acids using Ni(OTf)2 as a catalyst. A diverse range of mandelic acids and phenols undergo C-H/O-

SbCl3-catalyzed solvent-free Friedel–Crafts reaction of phenols with mandelic acids to 3-aryl benzofuran-2(3H)-ones: Synthesis of spirocyclic 2,3-dihydrobenzofuran-2-ones

A facile, SbCl3-catalyzed, one-pot, tandem Friedel–Crafts/lactonization reaction of phenols and mandelic acids has been developed under solvent-free conditions to afford 3-aryl benzofuran-2(3H)-ones in good to high yields (52–90%). Additionally

NOVEL SPIRO KETONE AND CARBOXYLIC ACID DERIVATIVES AS SPECIFIC INHIBITORS FOR (PO3H2) SER/(PO3H2)THR-PRO-SPECIFIC PEPTIDYL-PROLYL-CIS/TRANS-ISOMERASES

The invention provides new spiro and carboxylic acid derivatives, pharmaceutically compositions comprising them and their use for the preparation of pharmaceutical compositions.