1037176-13-8

Basic information

• Product Name: 3-N-benzoyl-3',5'-di-O-benzoyl-5-(4-fluorobutyl)-2'-deoxy-2'-fluoroarabinouridine
• Synonyms: 3-N-benzoyl-3',5'-di-O-benzoyl-5-(4-fluorobutyl)-2'-deoxy-2'-fluoroarabinouridine
• CAS NO: 1037176-13-8
• Molecular Weight: 632.618
• Mol File: 1037176-13-8.mol

Chemical Properties

• CAS DataBase Reference: 3-N-benzoyl-3',5'-di-O-benzoyl-5-(4-fluorobutyl)-2'-deoxy-2'-fluoroarabinouridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-N-benzoyl-3',5'-di-O-benzoyl-5-(4-fluorobutyl)-2'-deoxy-2'-fluoroarabinouridine(1037176-13-8)
• EPA Substance Registry System: 3-N-benzoyl-3',5'-di-O-benzoyl-5-(4-fluorobutyl)-2'-deoxy-2'-fluoroarabinouridine(1037176-13-8)

Safety Data

• Hazardous Substances Data: 1037176-13-8(Hazardous Substances Data)

Upstream product

• 1037176-28-5 (4-fluorobutyl)zinc(II) bromide 
• 157428-24-5 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-N³-benzoyl-5-iodouracil 
• 462-72-6 4-bromo-1-fluorobutane 

Relevant articles and documents

Synthesis and in vitro evaluation of 5-[18F]fluoroalkyl pyrimidine nucleosides for molecular imaging of herpes simplex virus type 1 thymidine kinase reporter gene expression

Two novel series of 5-fluoroalkyl-2′-deoxyuridines (FPrDU, FBuDU, FPeDU) and 2′-fluoro-2′-deoxy-5-fluoroalkylarabinouridines (FFPrAU, FFBuAU, FFPeAU) that have three, four, or five methylene units (propyl, butyl, or pentyl) at C-5 were prepared and tested

Synthesis of 5-fluoroalkylated pyrimidine nucleosides via Negishi cross-coupling

(Chemical Equation Presented) 5-Fluoroalkylated pyrimidine nucleosides (1) have potential as therapeutic agents and molecular imaging agents targeting HSV1-tk suicide gene therapy. Thus, straightforward preparation of 5-fluoroalkylated nucleoside derivati