1037204-01-5Relevant academic research and scientific papers
One-Pot Three-Component Synthesis of 2-Methyl-3-aminobenzofurans Using Calcium Carbide as a Concise Solid Alkyne Source
Ma, Xiaolong,Wang, Zhiqiang,Liu, Zhenrong,Li, Zheng
, p. 2990 - 2994 (2021)
A one-pot three-component method for the synthesis of 2-methyl-3-aminobenzofurans using calcium carbide as a concise solid alkyne source, and salicylaldehydes and secondary amines as starting materials is described. This protocol has salient feature of the use of inexpensive, abundant and easy-to-handle alkyne source, avoiding the use of inflammable and explosive acetylene gas as an original alkyne source. In addition, step economy, satisfactory yield, and simple work-up procedure are also advantages of this route.
