103724-87-4

Upstream product

• 120647-24-7 ethyl N-{2-{4-[(2-oxocyclohexyl)methyl]phenyloxy}ethyl}carbamate 
• 6329-26-6 ethyl N-(2-chloroethyl)carbamate 
• 155854-14-1 2-<4-(2-aminoethoxy)benzyl>cyclohexan-1-one 
• 22081-10-3 2-(4-Hydroxybenzyl)-1-cyclohexanone 
• 116026-78-9 2-<4-(2-bromoethoxy)benzyl>-1-cyclohexanone 

Relevant academic research and scientific papers

Carbamate series of juvenoids: Variation of the O-alkyl substituent

By changing the O-alkyl substituents of the carbamate moiety of alkyl N-{2-{4-[(2-oxocyclohexyl)methyl]phenoxy}ethyl}carbamates and subsequent transformation of the oxo group in the cyclohexyl substituent, the juvenoids 1-20 were synthesized (Scheme). The methyl (1-4), propyl (9-12), isopropyl (13-16), and prop-2-ynylcarbamates (17-20) were subjected to biological screening on several non-related insect species (Tenebrio molitor, Galleria mellonella, Dysdercus cingulatus, and Pyrrhocoris apterus). Some of the juvenoids showed high biological activity and excellent selectivity with respect to target insect species (Table 2).

PREPARATION OF CARBAMATE DERIVATIVES OF 2-(4-HYDROXYBENZYL)-1-CYCLOHEXANONE WITH A JUVENOID ACTIVITY

The synthesis of four carbamate derivatives of 2-(4-hydroxybenzyl)-1-cyclohexanone displaying a juvenilizing effect in insects is described.The substances prepared have a greater stability and activity than their carba-analogues prepared earlier.