10373-78-1

Basic information

• Product Name: DL-CAMPHORQUINONE
• Synonyms: 7,7-trimethyl-3-dion(+/-)-bicyclo[2.2.1]heptane-1;Bicyclo[2.2.1]heptane-2,3-dione, 1,7,7-trimethyl-, (.+/-.)-;bicyclo[2.2.1]heptane-2,3-dione,1,7,7-trimethyl-;camphoquinone;camphoroquinone;RAC-CAMPHORQUINONE;(+/-)-CAMPHORQUINONE;CAMPHORQUINONE
• CAS NO: 10373-78-1
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.22
• EINECS: 233-814-1
• Product Categories: Bicyclic Monoterpenes;Biochemistry;Functional Materials;Photopolymerization Initiators;Terpenes;Building Blocks/Intermediates
• Mol File: 10373-78-1.mol
• Article Data: 20

Chemical Properties

• Melting Point: 197-203 °C(lit.)
• Boiling Point: 234.44°C (rough estimate)
• Flash Point: 82.965 °C
• Appearance: Yellow/Fine Crystalline Powder
• Density: 0.9817 (rough estimate)
• Vapor Pressure: 0.0817mmHg at 25°C
• Refractive Index: 1.4859 (estimate)
• Storage Temp.: 2-8°C
• Solubility: Soluble in ethanol, ethyl ether and benzene.
• BRN: 1909463
• CAS DataBase Reference: DL-CAMPHORQUINONE(CAS DataBase Reference)
• NIST Chemistry Reference: DL-CAMPHORQUINONE(10373-78-1)
• EPA Substance Registry System: DL-CAMPHORQUINONE(10373-78-1)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 10373-78-1(Hazardous Substances Data)

Usage

Chemical Properties

YELLOW FINE CRYSTALLINE POWDER

Uses

Different sources of media describe the Uses of 10373-78-1 differently. You can refer to the following data:
1. initiator for visible-light-cured dental acrylic-composite materials.
2. Camphorquinone derivative (i.e. carboxylated camphorquinone) is used as visible-light photoinitiator in biomedical applications. It is also used in dentistry and is often used in conjunction with hydrogen donating amine.
3. CQ-amines are used as a photo initiators for free radical polymerization. CQ was used as an initiator in the preparation of silver nanoparticle/silica/ polymer nanocomposites. Photopolymerization kinetics of dimethacrylates were studied using the CQ/amine initiator system.

General Description

Camphorquinone (CQ) absorbs UV radiation in the region of 200-300nm due to the Π?Π* transition and visible light (400-500nm) due to the n, Π* transition of the α-dicarbonyl chromophore.

Purification Methods

Purification is the same as for above enantiomers. [Huckel & Fichtig Justus Liebigs Ann Chem 628 81 1962, Evans et al. J Chem Soc 137 1939, Beilstein 7 I 325.]

InChI:InChI=1/C10H14O2/c1-9(2)6-4-5-10(9,3)8(12)7(6)11/h6H,4-5H2,1-3H3/t6-,10-/m1/s1

Upstream product

• 7519-74-6 thiocamphor 
• 17697-12-0 benzeneseleninic anhydride 
• 736109-58-3 1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 
• 14487-70-8 3-diazocamphor 
• 100-47-0 benzonitrile 
• 75-05-8 acetonitrile 
• 104319-35-9 DL camphor-10-thiazine dioxide 
• 663-17-2 camphorquinone monooxime 
• 76013-16-6 3-endo-(phenylseleninyl)camphor 
• 79532-63-1 1-(1-Ethoxy-3,7,7-trimethyl-2-oxo-bicyclo<2.2.1>heptyl)-4-phenyl-1,2,4-triazolidin-3,5-dion 
• 95589-30-3 (1S,2R,4R,4'R)-4'-Chloromethyl-4,7,7-trimethylbicyclo<2.2.1>heptane-2-spiro-2'-(1',3'-dioxolan)-3-one 
• 31571-14-9 (1R,E)-(+)-camphorquinone 3-oxime 
• 76-22-2 Camphor 
• 76-29-9 3-bromocamphor 

Downstream Products

• 595-29-9 camphoric anhydride 
• 15210-83-0 2,2,3-trimethyl-4-oxo-cyclohexanecarboxylic acid 
• 71681-63-5 3-o-tolylimino-bornan-2-one 
• 116865-63-5 (+/-)-3-((Ξ)-3-bromo-phenylimino)-bornan-2-one 
• 3278-94-2 homocamphorquinoline 
• 21488-68-6 (1R)-3exo-hydroxy-bornan-2-one 
• 10373-79-2 DL-3-endo-(4-Methyl-benzyl)-3-exo-hydroxy-bornan-2-on 
• 101980-80-7 1,2,2-trimethylcyclopentyl p-methylbenzyl ketone 
• 10373-80-5 DL-2-endo-(4-Methyl-benzyl)-2-exo-hydroxy-bornan-3-on 
• 101980-83-0 2,2,3-trimethylcyclopent-3-enyl p-methylbenzyl ketone 
• 101980-82-9 2,2-dimethyl-3-methylenecyclopentyl p-methylbenzyl ketone 
• 101980-84-1 cis-2,2,3-trimethylcyclopentyl p-methylbenzyl ketone 
• 101980-81-8 trans-2,3,3-trimethylcyclopentyl p-methylbenzyl ketone 
• 84831-92-5 5,6,7,8-tetrahydro-5,9,9-trimethyl-3-(3-nitrophenyl)-5,8-methano-1,2,4-benzotriazine 

Relevant articles and documents

Novel synthetic method of camphorquinone

The invention relates to a novel synthetic method of camphorquinone, which is a method for preparing camphorquinone from camphor in the presence of a catalyst. The invention further provides a methodfor preparing camphorquinone, which can effectively reduce the toxicity of the used catalyst and reflect the harm to the environment, and ensures a high yield of the reaction while simplifying the process flow. According to the method, clean energy microwave irradiation instead of conventional energy is utilized, so that the pollution of the reaction to the environment is greatly reduced while thereaction yield is ensured, and the purpose of green chemistry is met.

Method for producing camphorquinone by taking byproduct generated in camphor synthesis process as raw material

The invention provides a method for producing camphorquinone by taking a byproduct generated in the camphor synthesis process as a raw material, belonging to the technical field of organic synthesis.The byproduct 3-camphene ester generated in the synthesis process of camphor is used as a starting material to prepare high-purity camphorquinone through refining, saponification, dehydrogenation, condensation, hydrolysis and recrystallization steps. The method has the beneficial effects that the value of the byproduct generated in the camphor synthesis process is used, industrial wastes are reduced, wastes are changed into valuables, environmental pressure is reduced, a brand-new path for the synthesis of the camphorquinone is provided, no heavy metals are used in all process steps, truly nontoxic chemical synthesis of the camphorquinone is realized, and the method is an economic and environment-friendly production process.

SELECTIVELY POLYMERIZABLE COMPOSITIONS AND METHODS OF USE IN VIVO

Otologic materials and methods are provided. For example, a cell-adhesive, biodegradable hydrogel scaffold loaded with time-released drugs for repairing chronic tympanic membrane perforations is disclosed, methods of making same and administering same are provided. This hydrogel may promote vascular in-growth and epithelial cell growth of the tympanic membrane with the purpose of closing the perforation and providing a barrier between the external and middle ear. The hydrogel is initially a liquid polymer that only gels upon exposure to specific conditions, such as exposure to light. This scaffold may simultaneously induce repair of the tympanic membrane while preventing or alleviating middle ear infection, thus filling a void in current tympanic membrane perforation therapies.