103733-17-1Relevant academic research and scientific papers
Enantioselective One-Pot Synthesis of β-Lactams from Achiral 2-Pyridylthioesters and Aromatic Imines
Annunziata, Rita,Benaglia, Maurizio,Cinquini, Mauro,Cozzi, Franco
, p. 613 - 616 (2007/10/02)
The enolates derived from 2-pyridylthioesters by reaction with BCl3*SMe2 and enantiomerically pure aminoalcohols react with aromatic imines in an enantioselective fashion (ee up to 78percent) to afford β-lactams in a convenient one-pot procedure.
