103733-32-0

Usage

Uses

Used in Medicinal Chemistry and Pharmacology:
1,2,3,4-Tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid phenylmethyl ester hydrochloride is used as a potential therapeutic agent for its possible biological activities that could be beneficial in the treatment of certain conditions. However, further research and clinical studies are required to confirm its efficacy and safety for medical use.

Upstream product

• 82586-62-7 (S)‐6,7‐dimethoxy‐1,2,3,4-tetrahydroisoquinoline‐3‐carboxylate hydrochloride 
• 100-51-6 benzyl alcohol 
• 358627-67-5 (S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-(tert-butyloxycarbonyl)-3-isoquinolinecarboxylic acid 
• 617699-49-7 (S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-(tert-butyloxycarbonyl)-3-isoquinolinecarboxylic acid benzyl ester 

Relevant academic research and scientific papers

Preparation of chiral 1,2,3,4-tetrahydro-6,7-dialkoxy-3-isoquinolinecarboxylic acid and derivatives

The present invention relates to a process for the production of (S)-1,2,3,4-tetrahydro-6,7-dialkoxy-3-isoquinolinecarboxylic acid compounds (1) and their derivatives from Levodopa (L-Dopa). The ultimately prepared compounds are used as intermediates for, but not limited to, the preparation of substituted derivatives of 1,2,3,4-tetrahydro-6,7-dialkoxy-3-isoquinolinecarboxylic acid wherein R1is hydrogen, lower alkyl, C2-C12 acyl, or R1O together are methylenedioxy; R2is hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, aryl, substituted aryl, aralkyl or substituted aralkyl group; and R3is hydrogen, C2-C12 acyl group, benzyl, alkoxylcarbonyl group, or aralkoxyl carbonyl group.