1037515-64-2Relevant academic research and scientific papers
Fully orthogonally protected 2-deoxystreptamine from kanamycin
Aslam, M. Waqar,Busscher, Guuske F.,Weiner, David P.,De Gelder, Rene,Rutjes, Floris P. J. T.,Van Delft, Floris L.
, p. 5131 - 5134 (2008/12/22)
(Chemical Equation Presented) A fully orthogonally protected and enantiopure 2-deoxy-streptamine derivative is prepared in a few straightforward steps from commercially available kanamycin. Resolution of a sterically hindered diacetate was effected by a Verenium esterase and was followed by a chemoselective Staudinger reduction-acylation protocol.
