10376-48-4

Basic information

• Product Name: SHIONONE
• Synonyms: SHIONONE;2(1H)-Chrysenone,hexadecahydro-1,4b,6a,8,10a,12a-;hexamethyl-8-(4-methyl-3-pentenyl)-,(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-;18,19-Seco-D:A-friedolup-19-en-3-one;3β,5,8,17aβ-Tetramethyl-3-(4-methyl-3-pentenyl)-D-homo-5α-androstan-17-one;Shionone ,98%;21-Shionen-3-one;Shionone, 98%, from Aster tataricus L. f.
• CAS NO: 10376-48-4
• Molecular Formula: C30H50O
• Molecular Weight: 426.72
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 10376-48-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 161-162°
• Boiling Point: 485.6 °C at 760 mmHg
• Flash Point: 200.5 °C
• Appearance: /
• Density: 0.941 g/cm³
• Refractive Index: 1.497
• CAS DataBase Reference: SHIONONE(CAS DataBase Reference)
• NIST Chemistry Reference: SHIONONE(10376-48-4)
• EPA Substance Registry System: SHIONONE(10376-48-4)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 10376-48-4(Hazardous Substances Data)

Usage

Uses

Shionone is an effective inhibitor of human neutrophil elastase which may be used as a treatment for inflammatory lung diseases including H1N1 and SARS virus infections.

Definition

ChEBI: A tetracyclic triterpenoid that is perhydrochrysene which is substituted by methyl groups at positions 1, 4bbeta, 6aalpha, 8beta, 10abeta and 12a positions, by a 4-methylpent-3-enyl group t the 8alpha position, and with an oxo group at position 2.

InChI:InChI=1/C30H50O/c1-21(2)10-9-14-26(4)16-19-30(8)25-13-15-28(6)22(3)23(31)11-12-24(28)29(25,7)18-17-27(30,5)20-26/h10,22,24-25H,9,11-20H2,1-8H3/t22-,24+,25-,26+,27-,28+,29-,30+/m0/s1