1037683-01-4Relevant academic research and scientific papers
Catalytic asymmetric Stetter reaction onto vinylphosphine oxides and vinylphosphonates
Cullen, Steven C.,Rovis, Tomislav
supporting information; experimental part, p. 3141 - 3144 (2009/05/11)
(Chemical Equation Presented) An intramolecular Stetter reaction of vinylphosphine oxides and vinylphosphonates has been developed. Treatment of an aldehyde with a nucleophilic N-heterocyclic carbene catalyst allows for addition of an acyl anion equivalent into a vinylphosphine oxide or vinylphosphonate Michael acceptor in yields up to 99% and ee values up to 96%.
