103774-92-1

Basic information

• Product Name: cis-6-cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-benzopyran-3-ol
• CAS NO: 103774-92-1
• Molecular Weight: 286.331
• Mol File: 103774-92-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: cis-6-cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-benzopyran-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: cis-6-cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-benzopyran-3-ol(103774-92-1)
• EPA Substance Registry System: cis-6-cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-benzopyran-3-ol(103774-92-1)

Safety Data

• Hazardous Substances Data: 103774-92-1(Hazardous Substances Data)

Upstream product

• 103732-68-9 (3S,4S)-4-Azido-2,2-dimethyl-3-(tetrahydro-pyran-2-yloxy)-chroman-6-carbonitrile 
• 103774-94-3 (3S,4S)-4-Bromo-2,2-dimethyl-3-(tetrahydro-pyran-2-yloxy)-chroman-6-carbonitrile 
• 103732-70-3 (3R,4R)-4-Amino-2,2-dimethyl-3-(tetrahydro-pyran-2-yloxy)-chroman-6-carbonitrile 
• 103732-67-8 trans-4-bromo-6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ol 
• 65018-90-8 3,4-epoxy-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-carbonitrile 
• 103732-69-0 cis-4-<(4-chlorobutyryl)amino>-6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ol 
• 94470-67-4 cromakalim 

Relevant articles and documents

AN UNUSUAL HYDROXYL INVERSION MEDIATED BY DAST

Trans-3-hydroxy-4-(2-oxopyrrolidin-1-yl) benzopyrans have been shown to undergo inversion to cis-3-hydroxy-4-(2-oxopyrrolidin-1-yl) benzopyrans in moderate yield on treatment with diethylaminosulphur trifluoride (DAST).

Synthesis and antihypertensive activity of 4-(cyclic amido)-2H-1-benzopyrans

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