103796-62-9

Basic information

• Product Name: 1-METHYLINDOLIN-6-AMINE
• Synonyms: 1-METHYLINDOLIN-6-AMINE;UKRORGSYN-BB BBV-116752;1-Methyl-2,3-dihydro-1H-indol-6-ylamine
• CAS NO: 103796-62-9
• Molecular Formula: C₉H₁₂N₂
• Molecular Weight: 148.21
• Mol File: 103796-62-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 42-43 °C
• Boiling Point: 143-144 °C
• Appearance: /
• Density: 1.123±0.06 g/cm3(Predicted)
• PKA: 6.41±0.20(Predicted)
• CAS DataBase Reference: 1-METHYLINDOLIN-6-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYLINDOLIN-6-AMINE(103796-62-9)
• EPA Substance Registry System: 1-METHYLINDOLIN-6-AMINE(103796-62-9)

Safety Data

• Hazardous Substances Data: 103796-62-9(Hazardous Substances Data)

Usage

General Description

1-Methylindolin-6-amine is an organic compound with the molecular formula C9H10N2. It is a derivative of indole and an amine, containing a methyl group at the 1-position of the indoline ring. This chemical compound has potential applications in the field of medicinal chemistry and drug development due to its structural properties and potential biological activities. It is also used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Additionally, 1-Methylindolin-6-amine has been studied for its potential role as an inhibitor of specific enzymes and as a building block for the synthesis of diverse heterocyclic compounds for pharmaceutical purposes.

Upstream product

• 115210-53-2 1-methyl-6-nitroindoline 
• 19727-83-4 6-nitroindoline 

Relevant articles and documents

QUINAZOLINE DERIVATIVES FOR USE AGAINST CANCER

The invention concerns quinazoline derivatives of Formula (I) or a pharmaceutically-acceptable salt, solvate or pro-drug thereof, wherein each of p, R1, q, R2, R3, R4, R5, Ring A, X1, R6, r and R7 has any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders or in the treatment of disease states associated with angiogenesis and/or vascular permeability.

Vanilloid receptor ligands and their use in treatments

Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.